Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz +14 more
wiley +1 more source
Progress in RNA‐Targeted Therapeutics for Human Diseases
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source
Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen +8 more
wiley +1 more source
Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets
The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang +6 more
wiley +1 more source
Application of chitosan-based nanogels for dermal and transdermal delivery systems. [PDF]
Fard AS +3 more
europepmc +1 more source
Nanogels with volume phase transition for biomedical applications. [PDF]
Li Z, Yang X, Li Z.
europepmc +1 more source
Systematic design of polybasic nanogels: influence of hydrophobic monomers on tunable physicochemical and biological properties. [PDF]
Wagner AM +8 more
europepmc +1 more source
Enhanced Stability of O/W Pickering Emulsions Driven by Interfacial Adsorption of Whey Protein Nanogels. [PDF]
Yu Z, He F, Ke L, Jacquier JC.
europepmc +1 more source
A carbonic anhydrase-based nanogel for cyanobacterial growth enhancement. [PDF]
Stoeckle M +6 more
europepmc +1 more source
From chemistry to targeted cancer therapy: potent benzimidazole-1,2,3-triazole hybrid-loaded nanogels against breast and colorectal malignancies. [PDF]
Malebari AM +10 more
europepmc +1 more source

