Results 61 to 70 of about 12,558 (240)

Synthesis of cross-linked poly(acrylic acid) nanogels in an aqueous environment using precipitation polymerization: unusually high volume change [PDF]

Royal Society Open Science, 2019
For the first time, by using precipitation polymerization in an aqueous solution, a cross-linked poly(acrylic acid)—(pAA) nanogel was synthesized.
Marcin Mackiewicz, Zbigniew Stojek, Marcin Karbarz   +2 more
doaj   +1 more source

Reactive precursor particles as synthetic platform for the generation of functional nanoparticles, nanogels, and microgels [PDF]

, 2019
Precise control of the chemical functionality of polymer nanoparticles is a key requirement in tailoring their (dynamic) colloidal properties toward advanced applications.
Gruber, Alexandra, Klinger, Daniel, Navarro, Lucila   +2 more
core   +1 more source

A Virus‐Mimetic Nanogel Vehicle [PDF]

Angewandte Chemie International Edition, 2008
Viruses infect specific cells within host organisms, replicate, destroy the cells, and spread from cell to cell in infectious cycles, thus causing disease.[1] These viral properties have inspired synthetic designs of various delivery vehicles,[2–6] particularly for toxic anticancer agents that exhibit numerous side effects. Drug-delivery vehicles often
Eun Seong, Lee, Dongin, Kim, Yu Seok, Youn, Kyung Taek, Oh, You Han, Bae   +4 more
openaire   +2 more sources

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

Management of Enterococcus faecalis associated endodontic infection using gold nanogel: An in-vitro study

Saudi Dental Journal
This study evaluates the antimicrobial efficacy of gold nanogel as an endodontic medicament against Enterococcus faecalis in persistent root canal infections. It investigates whether gold nanogel can serve as an effective and biocompatible alternative to
Omer Sheriff Sultan, Goh Chong Ming Jonathan, Seow Liang Lin, Fabian Davamani, Preena Sidhu, Minati Choudhury   +5 more
doaj   +1 more source

Development of a hybrid dextrin hydrogel encapsulating dextrin nanogel as protein delivery system [PDF]

, 2012
Dextrin, a glucose polymer with low molecular weight, was used to develop a fully resorbable hydrogel, without using chemical initiators. Dextrin was first oxidized (oDex) with sodium periodate and then cross-linked with adipic acid dihidrazide, a ...
Carvalho, Vera, Gama, F. M., Molinos, Maria, Silva, Dina M.   +3 more
core   +1 more source

Low nanogel stiffness favors nanogel transcytosis across an in vitro blood–brain barrier

Nanomedicine: Nanotechnology, Biology and Medicine, 2021
Transport of therapeutics across the blood-brain barrier (BBB) is a fundamental requirement for effective treatment of numerous brain diseases. However, most therapeutics (>500 Da) are unable to permeate through the BBB and do not achieve therapeutic doses. Nanoparticles (NPs) are being investigated to facilitate drug delivery to the brain.
Ribovski, Laís, de Jong, Edwin, Mergel, Olga, Zu, Guangyue, Keskin, Damla, van Rijn, Patrick, Zuhorn, Inge S.   +6 more
openaire   +3 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Cyclodextrin-responsive nanogel as an artificial chaperone for horseradish peroxidase [PDF]

, 2011
The thermal stabilization and refolding of horseradish peroxidase (HRP) upon heating were investigated using an artificial molecular chaperone consisting of cholesterol-bearing pullulan (CHP) nanogels.
Akiyoshi, Kazunari, Nomura, Yuta, Sasaki, Yoshihiro, Sawada, Shin-ichi   +3 more
core   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source