Results 91 to 100 of about 5,478 (212)

Polymersome‐Enabled Multimodal Delivery of Tobramycin and Doripenem for Targeted Eradication of Pseudomonas aeruginosa Biofilms in Chronic Rhinosinusitis

Small, EarlyView.
Schematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Amalie Kjær Andresen, Matteo Tollemeto, Alexander B. Cook, Claus Sternberg, Yudong Li, Claus Moser, Lars Jelsbak, Jan C. M. Van Hest, Anja Boisen, Line Hagner Nielsen   +9 more
wiley   +1 more source

Hierarchical Peptide Functionalized Titania Nanotubes: Improving Stability, Promoting Osteogenesis, and Reducing Infection Risk

Small, EarlyView.
The study demonstrates a dual‐level modification of titania nanotube surfaces through the covalent grafting of Fmoc‐FF dipeptides, followed by a secondary self‐assembled layer of FF dipeptide. This hierarchical strategy significantly enhances coating density and structural integrity without compromising the nano‐topographical and biochemical cues ...
Ramesh Singh, Ketul C Popat
wiley   +1 more source

HS‐AFM Reveals Hierarchical RNA Folding Driving Condensate Assembly and Material States

Small, EarlyView.
High‐speed atomic force microscopy reveals the nanoscale pathway of RNA condensate formation, from individual RNA folding to higher‐order assembly. Quantitative analyses of fusion dynamics and nanomechanical properties distinguish liquid‐like poly A condensates from solid‐like total RNA assemblies, providing a direct link between RNA self‐assembly and ...
S. M. Neaz Mahmud, Kenichi Umeda, Tamoghna Das, Nadia Shoukat, Noriyuki Kodera, Hanae Sato   +5 more
wiley   +1 more source

Nanomechanics of individual aerographite tetrapods

Nature Communications, 2017
Aerographite is a highly porous and lightweight carbon material obtained from hollow tubular tetrapod building units. Here, the authors present a comprehensive investigation of tetrapod deformation mechanisms which are at the core of aerographite ...
Raimonds Meija, Stefano Signetti, Arnim Schuchardt, Kerstin Meurisch, Daria Smazna, Matthias Mecklenburg, Karl Schulte, Donats Erts, Oleg Lupan, Bodo Fiedler, Yogendra Kumar Mishra, Rainer Adelung, Nicola M. Pugno   +12 more
doaj   +1 more source

Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties

Small, EarlyView.
The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey, Alexander J. Bryer, Juan R. Perilla   +2 more
wiley   +1 more source

Effects of Oxygen Pressure on the Microstructures and Nanomechanical Properties of Samarium-Doped BiFeO₃ Thin Films. [PDF]

Micromachines (Basel), 2023
Gao CS, Jian SR, Le PH, Chou WC, Juang JY, Chang HW, Lin CM.   +6 more
europepmc   +1 more source

Unveiling Van Der Waals Forces and Associated Hamaker Constants Across the Nanomaterial Landscape With Advanced Atomic Force Microscopy

Small Methods, EarlyView.
Van der Waals interactions are reviewed through the lens of advanced atomic force microscopy, highlighting recent progress in nanoscale quantification of Hamaker constants. Emerging methodologies enable high‐resolution mapping of intermolecular forces in 2D materials and biological systems, bridging experimental measurements with quantum‐informed ...
Amir Farokh Payam, Horacio V. Guzman, Alexandre Tkatchenko   +2 more
wiley   +1 more source

Retracted: Preparation of Porous Ceramic Building Decoration Materials by Foaming Method and Research on Nanomechanical Properties. [PDF]

Int J Anal Chem, 2023
Chemistry IJOA.
europepmc   +1 more source

Spatial Characterization of the Human Meniscus: Bridging Biomechanics and Biochemistry Using Atomic Force Microscopy Micro‐Indentation and Mass Spectrometry Imaging

Small Methods, EarlyView.
A multimodal imaging approach combines AFM micro‐indentation and MALDI mass spectrometry imaging on the same fresh‐frozen human meniscus section to directly associate microscale mechanics with molecular composition. Collagen‐rich regions exhibit increased stiffness, whereas zones enriched in other extracellular matrix proteins are mechanically less ...
Aleksandra N. Lebedeva, Martin Handelshauser, Orestis G. Andriotis, Lena Hirtler, Martina Marchetti‐Deschmann, Philipp J. Thurner   +5 more
wiley   +1 more source

Revealing the static and dynamic nanomechanical properties of diatom frustules-Nature's glass lace. [PDF]

Sci Rep, 2023
Cvjetinovic J, Luchkin SY, Statnik ES, Davidovich NA, Somov PA, Salimon AI, Korsunsky AM, Gorin DA.   +7 more
europepmc   +1 more source