Results 191 to 200 of about 102,003 (257)

Assessment of In Vitro Nano‐Cytotoxicity Through Fluorescence Microscopy via Neural Network‐Based Live/Dead Cell Classification

Advanced Intelligent Systems, EarlyView.
FluoAI is a two‐stage, label‐free method for quantifying nanomaterial‐induced cytotoxicity from conventional fluorescence microscopy images. Mask R‐CNN segmentation and DenseNet‐121 classification provide rapid live/dead classification matching human accuracy.
Ugur C. Topkiran, Ali Gasimli, Lal Durmaz, Diya Vashani, Himish Paul, Giridhar R. Akkaraju, Anton V. Naumov   +6 more
wiley   +1 more source

Nanomedicine-based sensitization and resistance reversal in immunotherapy of clear cell renal cell carcinoma: from tumor microenvironment to precision delivery. [PDF]

Med Oncol
Ma J, Qiang Z, Xie W, Jiao L, Mi L, Ma K, Yang Z, Chen G.   +7 more
europepmc   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Why is nanomedicine needed to treat disorders of the endometrium? [PDF]

Clin Transl Med
Abbasi S, Ensign LM.
europepmc   +1 more source

Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography

Advanced NanoBiomed Research, EarlyView.
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley   +1 more source

Intranasal Biodegradable Nanomedicine for Epilepsy Management: Targeting the Brain Beyond the Blood-Brain Barrier. [PDF]

Int J Nanomedicine
Gilani SJ, Sultan AM, Alshawwa SZ, Rizwanullah M.   +3 more
europepmc   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

Advanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

Bibliometric analysis of research trends on nanotechnology applications in atherosclerosis. [PDF]

Discov Nano
Zhang X, Ji B, Liu Z, Zhang Y, Wang G, Zhao Y, Zhang Y.   +6 more
europepmc   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Nanomedicine in 2026: Illustrative Quantitative Analyses of EPR Heterogeneity, Clinical Trial Attrition, and Emerging Horizons for Active Nanotherapeutics. [PDF]

Int J Nanomedicine
Fayez SM.
europepmc   +1 more source