Results 31 to 40 of about 74,551 (265)

Functional peptide-loaded gelatin nanoparticles as eyedrops for cornea neovascularization treatment

, 2023
[[abstract]]Background: Corneal neovascularization (NV) is a process of abnormal vessel growth into the transparent cornea from the limbus and can disturb the light passing through the cornea, resulting in vision loss or even blindness.
Chu, YC;Fang, HW;Wu, YY;Tang, YJ;Hsieh, EH;She, YZ;Chang, CY;Lin, IC;Chen, YJ;Liu, GS;Tseng, CL
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Endocytosis of nanomedicines

Journal of Controlled Release, 2010
Novel nanomaterials are being developed to improve diagnosis and therapy of diseases through effective delivery of drugs, biopharmaceutical molecules and imaging agents to target cells in disease sites. Such diagnostic and therapeutic nanomaterials, also termed “nanomedicines”, often require site-specific cellular entry to deliver their payload to sub ...
Kabanov, Alexander V., Sahay, Gaurav, Alakhova, Daria Y.   +2 more
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Bypassing the EPR effect with a nanomedicine harboring a sustained-release function allows better tumor control

, 2015
The current enhanced permeability and retention (EPR)-based approved nanomedicines have had little impact in terms of prolongation of overall survival in patients with cancer. For example, the two Phase III trials comparing Doxil®, the first nanomedicine
Liu, Ren Shyan, Shen, Biing Jiun, Lu, Maggie, He, Chun Lin, Wei, Yau Huei, Hsu, Yen Mei, Liu, Chih Peng, Chuang, Chi Mu, Shen, Yao An, Shyu, Ing Luen, Liang, Hsiang Fa   +10 more
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Nanoinformatics: developing new computing applications for nanomedicine

, 2012
Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges.
Maojo, V., Hussein, R., Milanesi, L., Koch, Sabine, Graf, N, Antoine Geissbuhler, Diana De la Iglesia, Crespo, J, Fritts, Martin, Fernando Martin-Sanchez, Miguel Garcia-Remesal, Guillermo De la Calle, Pazos, A., Grangeat, P., Josipa Kern, Moustakis, Vassilis, Pazos, A, Potamias, G, Jose Crespo, Norbert, Graf, David Perez-Rey, Kern, Josipa, Kern, J, Anguita, A, Sanz, F, Perez-Rey, D, Victoria Lopez-Alonso, Fritts, M, Norbert Graf, Baker, Nathan, Hermosilla, I ., Facelli, J C, Moustakis, V, Geissbuhler, A., Crespo, Jose, De la Iglesia, D., Potamias, George, De la Calle, Guillermo, Gonzalez-Nilo, Fernando, Casimir Kulikowski, Cachau, R.E., Koch, S, Iglesia Jimenez, Diana de la, Fritts, M., De la Iglesia, D, Otero, P, Hermosilla, Isabel, Mitchell, Joyce A., Facelli, Julio C., Perez Rey, David, Yannick Legre, Anguita, A., Martín-Sánchez, Fernando, Otero, Paula, Pierre Grangeat, Sanz, F., Sabine Koch, Ghazal, Peter, Moustakis, V., Anguita, Alberto, García Remesal, Miguel, Calle, Guillermo de la, Cachau, R E, Martin-Sanchez, F, Martín Sánchez, Fernando, Vassilis Moustakis, Peter Ghazal, Legre, Y., Milanesi, L, Baker, N, Kulikowski, C, Garcia-Remesal, Miguel, Cachau, Raul E., Rada Hussein, Crespo, J., Hussein, Rada, Koch, S., Lopez-Campos, G., Benitez, S.E., Ferran Sanz, Kulikowski, C., Martin Fritts, Barreiro, J M, Benitez, S E, De la Calle, G., Benitez, Sonia E., Jose Maria Barreiro, Guillermo Lopez-Campos, Paula Otero, Garcia-Remesal, M, Pazos Sierra, Alejandro, Maojo Garcia, Victor Manuel, Maojo, Victor, Ghazal, P., Graf, N., Fernando Gonzalez-Nilo, Grangeat, Pierre, Kern, J., Hussein, R, Hermosilla, I, Otero, P., Legre, Yannick, Barreiro, J.M., Legre, Y, Martin-Sanchez, F., González-Nilo, F., Sonia E. Benitez, Pazos, Alejandro, Raul E. Cachau, Baker, N., Maojo, V, Lopez-Campos, G, Maria Barreiro, Jose, Perez-Rey, David, Cristian Munteanu, Geissbuhler, Antoine, Milanesi, Luciano, Lopez-Alonso, V., Julio C. Facelli, Victor Maojo, Mitchell, J A, Munteanu, C, González-Nilo, Fernando D., Graf, Norbert, Garcia-Remesal, M., Gonzalez-Nilo, F, Anguita Sanchez, Alberto, Iglesia, Diana de la, Luciano Milanesi, Joyce A. Mitchell, De la Calle, G, De la Iglesia, Diana, Mitchell, J.A., Kulikowski, Casimir, Barreiro, José María, Munteanu, C., George Potamias, Sanz, Ferran, Perez-Rey, D., Nathan Baker, Grangeat, P, Munteanu, Cristian-Robert, Alejandro Pazos, Barreiro Sorrivas, Jose Maria, Potamias, G., Crespo del Arco, Jose, Munteanu, Cristian, Alberto Anguita, Lopez-Alonso, Victoria, Facelli, J.C., Isabel Hermosilla, Lopez-Alonso, V, Ghazal, P, Lopez-Campos, Guillermo   +153 more
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Chimeric Peptide Engineered Nanomedicine for Synergistic Suppression of Tumor Growth and Therapy-Induced Hyperlipidemia by mTOR and PCSK9 Inhibition

, 2023
Chemotherapy-induced side effects restrain anti-tumor efficiency, with hyperlipidemia being the most common accompanying disease to cause treatment failure.
Hua Cai, Wei Zhang, Jianing Chi, Ruixin Wang, Shiying Li, Lin Xu, Linping Zhao, Hong Cheng, Rongrong Zheng, Ningxia Wu, Jiaman Hu, Ali Chen   +11 more
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Nanomedicine and immunotherapy [PDF]

Expert Review of Vaccines, 2010
. The fundament for this tech-nology was probably laid even earlier by Paul Ehrlich and other visionary scientists in the beginning of the 20th Century. In his hypothesis of the infamous ‘Zauberkugel’, or ‘magic bullet’, an idea said to be inspired by Carl Maria von Weber’s opera ‘Der Freischutz’, Ehrlich described a vector sys-tem able to specifically
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The success of nanomedicine [PDF]

Nano Today, 2020
In recent years, the promise and prospects of nanomedicine have been controversially discussed. We here argue that nanomedicine has undeniably been successful, not only academically and preclinically, but also industrially and clinically. To ensure that we keep on making progress, we have to move away from over-focusing on nano and on materials ...
Lammers, Twan, Ferrari, Mauro
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The Nanomedicines Alliance: An Industry Perspective on Nanomedicines

Journal of Nanomedicine & Nanotechnology, 2014
The field of nanomedicines has expanded significantly in recent years in the breadth of compounds under development as well as in the types of technology that are being applied to generate nanomedicines. The pathway to licensure of new nanomedicines is sufficiently well defined by existing regulations and guidance.
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Nanomedicine: A systems engineering approach

, 2009
This book offers a fundamental and comprehensive overview of nanomedicine from a systems engineering perspective, making it the first book in the field of quantitative nanomedicine based on systems theory.
Zhang, Mingjun, Xi, Ning
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Polymer nanomedicines

Advanced Drug Delivery Reviews, 2020
Polymer nanomedicines (macromolecular therapeutics, polymer-drug conjugates, drug-free macromolecular therapeutics) are a group of biologically active compounds that are characterized by their large molecular weight. This review focuses on bioconjugates of water-soluble macromolecules with low molecular weight drugs and selected proteins.
Jindřich, Kopeček, Jiyuan, Yang
openaire   +3 more sources