Results 31 to 40 of about 72,557 (166)
The nanomedicine landscape of South Africa
Nanotechnology Reviews, 2017 Nanomedicine is one of the most exciting applications of nanotechnology and promises to address several of mankind’s healthcare needs. South Africa is one of the countries engaged in nanomedicine research and product development on the African continent.
Dube Admire, Ebrahim Naushaad
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Journal of Controlled Release, 2010 Novel nanomaterials are being developed to improve diagnosis and therapy of diseases through effective delivery of drugs, biopharmaceutical molecules and imaging agents to target cells in disease sites. Such diagnostic and therapeutic nanomaterials, also termed “nanomedicines”, often require site-specific cellular entry to deliver their payload to sub ...
Kabanov, Alexander V. +2 more
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Advanced Drug Delivery Reviews, 2020 Polymer nanomedicines (macromolecular therapeutics, polymer-drug conjugates, drug-free macromolecular therapeutics) are a group of biologically active compounds that are characterized by their large molecular weight. This review focuses on bioconjugates of water-soluble macromolecules with low molecular weight drugs and selected proteins.
Jindřich, Kopeček, Jiyuan, Yang
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RNA BiologyThe current letter to the editor describes the presence of RNA byproducts in small-scale in vitro transcription (IVT) reactions as evaluated by capillary gel electrophoresis, asymmetric flow field flow fractionation, immunoblotting, cell-free translation
Combes Francis +6 more
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Organ-on-a-chip platforms for accelerating the evaluation of nanomedicine
Bioactive Materials, 2021 Nanomedicine involves the use of engineered nanoscale materials in an extensive range of diagnostic and therapeutic applications and can be applied to the treatment of many diseases.
Xi Chen +3 more
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Nanomedicine in Chemoradiation [PDF]
Therapeutic Delivery, 2013 Chemoradiotherapy, the concurrent administration of chemotherapy and radiotherapy, is a treatment paradigm in oncology. It is part of the standard of care and curative treatment of many cancers. Given its importance, one of the primary goals of cancer research has been to identify agents and/or strategies that can improve the therapeutic index of ...
Seth M, Miller, Andrew Z, Wang
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Supramolecular nanostructure mimics GDNF trophic effects in vitro on human dopaminergic neurons
npj Regenerative MedicinePeptide-based supramolecular nanostructures offer a versatile platform with substantial promise for clinical translation in regenerative medicine.
Oscar A. Carballo-Molina +12 more
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Applied and Environmental MicrobiologyA novel compound denoted MBL-AB01 was isolated from a marine Actinoalloteichus, which belongs to a rare and underexplored class of Actinobacteria. This work demonstrates that the novel compound MBL-AB01 shows very high activity in vitro against six ...
Kristin Fløgstad Degnes +14 more
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Drug Delivery, 2018 Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the ...
Diana Rafael +12 more
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Transdermal delivery of allopurinol-loaded nanostructured lipid carrier in the treatment of gout
BMC Pharmacology and Toxicology, 2022 Background Allopurinol (ALP), a xanthine oxidase inhibitor, is a first line drug for the treatment of gout and hyperuricemia. Being the member of BCS class II drugs, ALP has solubility problem, which affects its bioavailability.
Zakir Ali +8 more
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