Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin
Molecules, 2019 Two novel nanomicellar formulations were developed to improve the poor aqueous solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and mixed nanomicelles combining Soluplus with d-α-tocopherol polyethylene glycol
Vieri Piazzini +2 more
exaly +3 more sources
An in vivo study on sonodynamic effects mediated by nanomicelles containing PpIX as a sonosensitizing agent [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Sonodynamic therapy (SDT) is a promising non-invasive adjuvant approach for treating accessible tumors, requiring ultrasound (US) waves, sonosensitizing molecules, and oxygen.
Maryam Bakhshizadeh +5 more
doaj +2 more sources
From design to Deployment: The innovative role of nanomicelles in targeted ophthalmic therapeutics [PDF]
Materials Today BioDelivering medications to targeted lesions poses significant challenges due to the unique anatomical structure and physical barriers of the eyeball. Polymer nanomicelles are spontaneously assembled from surfactants and amphiphilic polymers, encapsulating
Mengli Sun +11 more
doaj +2 more sources
Biomimetic tumor cell membrane-camouflaged nanomicelles for synergistic chemo-immunotherapy of Triple-negative breast cancer [PDF]
Materials Today BioTriple-negative breast cancer (TNBC) remains a clinical challenge due to its aggressive nature. Conventional chemo-immunotherapy suffers from poor tumor targeting and systemic toxicity, necessitating advanced delivery systems for synergistic drug ...
Xiaoman Xu +9 more
doaj +2 more sources
Nanotechnology-Driven Strategy Against SARS-CoV-2: Pluronic F127-Based Nanomicelles with or Without Atazanavir Reduce Viral Replication in Calu-3 Cells [PDF]
VirusesDespite extensive efforts, no highly effective antiviral molecule exists for treating moderate and severe COVID-19. Nanotechnology has emerged as a promising approach for developing novel drug delivery systems to enhance antiviral efficacy.
Eduardo Ricci-Junior +10 more
doaj +2 more sources
Integrating machine-learning and nanotechnology to quantify pH-modulated oxaliplatin release [PDF]
Scientific ReportsThe purpose of this work was to formulate and characterize pH-sensitive, surfactant-based nanomicelles for the targeted delivery of Oxaliplatin to breast cancer cells. A secondary aim was to utilize machine learning (ML) models to interpolate and dissect
Sonia Fathi-karkan +2 more
doaj +2 more sources
In vitro and in vivo evaluation of photo-induced antileishmanial activity of indocyanine green-loaded nanomicelles [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Due to its low toxicity and high absorbance in the range of 650 to 900 nm, indocyanine green (ICG) has garnered significant attention for its applications in photodynamic therapy (PDT) and photothermal therapy (PTT).
Shirin Jalili +5 more
doaj +2 more sources
Precise Control of the in vivo Fate of Nanomicelles Efficiently Treats Advanced Rheumatoid Arthritis via EGFR/JNK/MMP9 Pathway [PDF]
International Journal of NanomedicineNa Jia,1 Yunzhen Gao,2 Lan Yang,3 Yani Xu,2 Zhirong Zhang,2 Jingwen Wang,1 Ling Zhang3,4 1Department of Pharmacy, Xijing Hospital, The Fourth Military Medical University, Xi’an, 710032, People’s Republic of China; 2Key Laboratory of Drug Targeting and ...
Jia N +6 more
doaj +2 more sources
Hyaluronan-based theranostic nanomicelles for breast cancer-targeting and anticancer drug delivery
Materials & Design, 2023 Integration of diagnostic and therapeutic modalities into a single nanoplatform can play an important role in personalized cancer therapy. In this work, an all-in-one theranostic nanoplatform (HPCT nanomicelles) for breast cancer was fabricated, composed
Yibin Yu +4 more
doaj +1 more source
Molecules, 2021 Avian leukosis virus subgroup J (ALV-J) is an immunosuppressive virus which has caused heavy losses to the poultry breeding industry. Currently, there is no effective medicine to treat this virus.
Yuhao Sun +7 more
doaj +1 more source