Results 51 to 60 of about 935,118 (318)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Agriculture and Nanoparticles

open access: yes, 2020
Herbal, animal and agricultural activities that have been applied to meet human needs in harmony with nature throughout human history have not harmed the ecosystem and have not caused environmental problems. However, the current ecosystem balance continues to deteriorate as a result of classical agricultural practices to get more products from the unit
Altindal, Nüket, Altındal, Demet
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Physicochemical characterization of combustion generated inorganic nanoparticles [PDF]

open access: yes, 2008
Combustion generated particulate matter is widely recognized to be the major pollutant in urban areas because of stationary combustor and vehicular traffic sources. Particularly the ultrafine fraction was proven to have the highest impact on human health
Carbone, Francesco
core  

Nanoparticles in the clinic [PDF]

open access: yesBioengineering & Translational Medicine, 2016
AbstractNanoparticle/microparticle‐based drug delivery systems for systemic (i.e., intravenous) applications have significant advantages over their nonformulated and free drug counterparts. For example, nanoparticle systems are capable of delivering therapeutics and treating areas of the body that other delivery systems cannot reach.
Anselmo, Aaron C., Mitragotri, Samir
openaire   +2 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Plasmonic effects upon optical trapping of metal nanoparticles [PDF]

open access: yes, 2010
Optical trapping of metal nanoparticles investigates phenomena at the interface of plasmonics and optical micromanipulation. This thesis combines ideas of optical properties of metals originating from solid state physics with force mechanism resulting ...
Dienerowitz, Maria
core  

Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis [PDF]

open access: yes, 2003
Superparamagnetic iron oxide nanoparticles have been used for many years as magnetic resonance imaging contrast agents or in drug delivery applications.
Berry, C.C.   +3 more
core   +1 more source

Neuromodulation with nanoparticles [PDF]

open access: yesScience, 2017
Ultrasonic drug uncaging shows potential for noninvasive manipulation of the ...
openaire   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

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