Chitosan-Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies [PDF]
Mediators of Inflammation, 2020 Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation and immunogenic cell death of ...
Claudia Robles-Planells +14 more
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Cyclodextrin-Modified Nanomaterials for Drug Delivery: Classification and Advances in Controlled Release and Bioavailability [PDF]
Pharmaceutics, 2021 In drug delivery, one widely used way of overcoming the biopharmaceutical problems present in several active pharmaceutical ingredients, such as poor aqueous solubility, early instability, and low bioavailability, is the formation of inclusion compounds ...
Daniel Andrés Real +6 more
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Functionalization of Gold Nanostars with Cationic β-Cyclodextrin-Based Polymer for Drug Co-Loading and SERS Monitoring [PDF]
Pharmaceutics, 2021 Gold nanostars (AuNSs) exhibit modulated plasmon resonance and have a high SERS enhancement factor. However, their low colloidal stability limits their biomedical application as a nanomaterial.
Orlando Donoso-González +7 more
doaj +2 more sources
Label-Free Oligonucleotide-Based SPR Biosensor for the Detection of the Gene Mutation Causing Prothrombin-Related Thrombophilia [PDF]
Sensors, 2020 Prothrombin-related thrombophilia is a genetic disorder produced by a substitution of a single DNA base pair, replacing guanine with adenine, and is detected mainly by polymerase chain reaction (PCR).
Rodrigo Sierpe +2 more
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Adoptive NK Cell Transfer as a Treatment in Colorectal Cancer Patients: Analyses of Tumour Cell Determinants Correlating With Efficacy In Vitro and In Vivo [PDF]
Frontiers in Immunology, 2022 BackgroundColorectal cancer (CRC) is a heterogeneous disease with variable mutational profile and tumour microenvironment composition that influence tumour progression and response to treatment.
Pilar M. Lanuza +32 more
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Determination of the Concentration of IgG against the Spike Receptor-Binding Domain That Predicts the Viral Neutralizing Activity of Convalescent Plasma and Serum against SARS-CoV-2 [PDF]
Biology, 2021 Several hundred millions of people have been diagnosed of coronavirus disease 2019 (COVID-19), causing millions of deaths and a high socioeconomic burden.
Llipsy Santiago +25 more
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All About (NK Cell-Mediated) Death in Two Acts and an Unexpected Encore: Initiation, Execution and Activation of Adaptive Immunity [PDF]
Frontiers in Immunology, 2022 NK cells are key mediators of immune cell-mediated cytotoxicity toward infected and transformed cells, being one of the main executors of cell death in the immune system.
Ariel Ramírez-Labrada +24 more
doaj +2 more sources
Microbiota and Lung Cancer. Opportunities and Challenges for Improving Immunotherapy Efficacy [PDF]
Frontiers in Oncology, 2020 The advances in molecular biology and the emergence of Next Generation Sequencing (NGS) have revealed that microbiome composition is closely related with health and disease, including cancer.
Maitane Ocáriz-Díez +28 more
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Intraperitoneal exposure to nano/microparticles of fullerene (C₆₀) increases acetylcholinesterase activity and lipid peroxidation in adult zebrafish (Danio rerio) brain. [PDF]
Biomed Res Int, 2013 Even though technologies involving nano/microparticles have great potential, it is crucial to determine possible toxicity of these technological products before extensive use. Fullerenes C60 are nanomaterials with unique physicochemical and biological properties that are important for the development of many technological applications.
Dal Forno GO +10 more
europepmc +2 more sources
Photodynamic Therapy and Antibacterial Activities of a Novel Synthesized Quaternary Zn-Cu-In-S/ZnS QDs- mTHPP Porphyrin Conjugate [PDF]
International Journal of Nanomedicine, 2022 Ncediwe Tsolekile,1– 3 Sundararajan Parani,2,3 Erenilda Ferreira de Macedo,4 Thabang Calvin Lebepe,2,3 Rodney Maluleke,2,3 Vuyelwa Ncapayi,2,3 Mangaka Clara Matoetoe,1 Sandile Phinda Songca,5 Katia Conceição,6 Dayane Batista Tada,4 Oluwatobi Samuel ...
Tsolekile N +10 more
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