Results 21 to 30 of about 146,225 (252)
Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure
Objective: Diabetes is characterized by pancreatic β-cell dedifferentiation. Dedifferentiating β cells inappropriately metabolize lipids over carbohydrates and exhibit impaired mitochondrial oxidative phosphorylation. However, the mechanism linking the β-
Jason Fan +11 more
doaj +1 more source
Heterobimetallic Janus Catalysts for the One‐Pot Synthesis of Polar‐Apolar Block Copolymers
Heterobimetallic Janus catalysts act as bifunctional initiators, combining two distinct polymerisation mechanisms in one pot to deliver well‐defined apolar‐polar block copolymers. Combining Earth abundant Ti and Al catalysts for respective α‐olefin and lactone polymerisation, the orthogonal activity is enabled by unprecedented initiation from a Ti ...
Raju Chambenahalli +2 more
wiley +2 more sources
FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution
Background and Aims: Stomach cells can be converted to insulin-producing cells by Neurog3, MafA, and Pdx1 overexpression. Enteroendocrine cells can be similarly made to produce insulin by the deletion of FOXO1.
Wendy M. McKimpson +6 more
doaj +1 more source
Objective: Murine-specific muricholic acids (MCAs) are reported to protect against obesity and associated metabolic disorders. However, the response of mice with genetic depletion of MCA to an obesogenic diet has not been evaluated.
Antwi-Boasiako Oteng +3 more
doaj +1 more source
The induction of brown-like adipocyte development in white adipose tissue (WAT) confers numerous metabolic benefits by decreasing adiposity and increasing energy expenditure.
Kirstin A. Tamucci +3 more
doaj +1 more source
Optimising the NAOMI adaptive optics real-time control system [PDF]
This thesis describes the author's research in the field of Real-Time Control (RTC) for Adaptive Optics (AO) instrumentation. The research encompasses experiences and knowledge gained working in the area of RTC on astronomical instrumentation projects ...
Goodsell, S. J., Goodsell, S J
core
Phase‐Dependent Oxygen Defect Energetics in Epitaxial NbN/AlN/NbN Films
Phase dependent oxygen defect energetics in epitaxial δ‐NbN/AlN/δ‐NbN and β‐Nb2N/AlN/β‐Nb2N trilayers. Atomic‐scale analysis and first‐principles calculations reveal distinct oxygen incorporation pathways across NbN polymorphs. Layer resolved defect formation energies show that O is energetically more favorable within δ‐NbN electrodes, whereas in β ...
Prachi Garg +10 more
wiley +1 more source
Naomi Edward Randall interview [PDF]
Naomi Edward Randall attended Washington State Normal School (predecessor to Central Washington University) from 1932 to 1934.https://digitalcommons.cwu.edu/cwura_interviews/1038/thumbnail ...
Randall, Naomi Edward
core +1 more source
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr +7 more
wiley +1 more source

