Results 21 to 30 of about 146,225 (252)

Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure

open access: yesMolecular Metabolism, 2020
Objective: Diabetes is characterized by pancreatic β-cell dedifferentiation. Dedifferentiating β cells inappropriately metabolize lipids over carbohydrates and exhibit impaired mitochondrial oxidative phosphorylation. However, the mechanism linking the β-
Jason Fan   +11 more
doaj   +1 more source

Heterobimetallic Janus Catalysts for the One‐Pot Synthesis of Polar‐Apolar Block Copolymers

open access: yesAngewandte Chemie, EarlyView.
Heterobimetallic Janus catalysts act as bifunctional initiators, combining two distinct polymerisation mechanisms in one pot to deliver well‐defined apolar‐polar block copolymers. Combining Earth abundant Ti and Al catalysts for respective α‐olefin and lactone polymerisation, the orthogonal activity is enabled by unprecedented initiation from a Ti ...
Raju Chambenahalli   +2 more
wiley   +2 more sources

[Portrait of Naomi Brooker]

open access: yes, 1972
Naomi Brooker Spring 1972Portrait of Naomi Booker sitting at table.

core   +2 more sources

FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution

open access: yesGastro Hep Advances, 2022
Background and Aims: Stomach cells can be converted to insulin-producing cells by Neurog3, MafA, and Pdx1 overexpression. Enteroendocrine cells can be similarly made to produce insulin by the deletion of FOXO1.
Wendy M. McKimpson   +6 more
doaj   +1 more source

Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage

open access: yesMolecular Metabolism, 2021
Objective: Murine-specific muricholic acids (MCAs) are reported to protect against obesity and associated metabolic disorders. However, the response of mice with genetic depletion of MCA to an obesogenic diet has not been evaluated.
Antwi-Boasiako Oteng   +3 more
doaj   +1 more source

The dark side of browning

open access: yesProtein & Cell, 2017
The induction of brown-like adipocyte development in white adipose tissue (WAT) confers numerous metabolic benefits by decreasing adiposity and increasing energy expenditure.
Kirstin A. Tamucci   +3 more
doaj   +1 more source

Optimising the NAOMI adaptive optics real-time control system [PDF]

open access: yes, 2008
This thesis describes the author's research in the field of Real-Time Control (RTC) for Adaptive Optics (AO) instrumentation. The research encompasses experiences and knowledge gained working in the area of RTC on astronomical instrumentation projects ...
Goodsell, S. J., Goodsell, S J
core  

Phase‐Dependent Oxygen Defect Energetics in Epitaxial NbN/AlN/NbN Films

open access: yesAdvanced Science, EarlyView.
Phase dependent oxygen defect energetics in epitaxial δ‐NbN/AlN/δ‐NbN and β‐Nb2N/AlN/β‐Nb2N trilayers. Atomic‐scale analysis and first‐principles calculations reveal distinct oxygen incorporation pathways across NbN polymorphs. Layer resolved defect formation energies show that O is energetically more favorable within δ‐NbN electrodes, whereas in β ...
Prachi Garg   +10 more
wiley   +1 more source

Naomi Edward Randall interview [PDF]

open access: yes, 2006
Naomi Edward Randall attended Washington State Normal School (predecessor to Central Washington University) from 1932 to 1934.https://digitalcommons.cwu.edu/cwura_interviews/1038/thumbnail ...
Randall, Naomi Edward
core   +1 more source

A Novel Splice Variant in ERGIC1 Causes Arthrogryposis Multiplex Congenita—Characterization Using Urine‐Derived Cells

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr   +7 more
wiley   +1 more source

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