Results 41 to 50 of about 56,158 (254)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Guest‐Induced Activation of Multicolor Photoluminescence in Naphthalene Bisimide Liquid Crystals

Advanced Materials, EarlyView.
Supramolecular host–guest design in naphthalene bisimide liquid crystals activates charge‐transfer emission and enables continuous tuning of color (511–685 nm) and lifetime, spanning prompt fluorescence, TADF, and RTP. Electron‐rich guests and Pt(II) complexes modulate emissive states, while co‐assembled NBI complexes create an energy‐transfer cascade ...
Johannes Nowarra, Swadhin Garain, Matthias Stolte, Frank Würthner   +3 more
wiley   +1 more source

Molecular Insights on Binding Interactions of Cyclooxygenase and Lipoxygenase Activities on Malondialdehyde in Naphthalene-Exposed Wistar Rats

Acta Medica Bulgarica
Naphthalene (NA), a polycyclic aromatic hydrocarbon, is an environmental pollutant from different sources exhibiting toxicities via free radical generation.
Olaoye I., Akhigbe G., Awotula A., Oso B., Agboola O., Adebayo A., Banwo R.   +6 more
doaj   +1 more source

Antimicrobial screening and one-pot synthesis of 4-(substituted-anilinomethyl)-3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives

Journal of Pharmacy and Bioallied Sciences, 2014
Aim: Synthesis of series of 4-(substituted-anilinomethyl-3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives (4a-4k) and their in vitro antifungal and antibacterial screening.
Neelima Goel, Sushma Drabu, Obaid Afzal, Sandhya Bawa   +3 more
doaj   +1 more source

A new fluorescent chemosensor for detection of aluminium ions [PDF]

شیمی کاربردی روز, 2016
A new Schiff base system (H2L) were synthesized and characterized by using of 2-hydroxy-1-naphthaldehyde and 2,6-diaminopyridine. The influence of metal cations Cr3+, Mn2+, Co2+, Cs+, Al3+, K+, Zn2+, Ni2+, Hg2+, Ba2+, Cu2+, Mg2+, Na+, Ag+, Cd2+,  Pb2 ...
Reza Azadbakht, Tayyebe Almasi, Javad Khanabadi   +2 more
doaj   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Using a Zero‐Strain Reference Electrode to Distinguish Anode and Cathode Volume Changes in a Solid‐State Battery

Advanced Materials Interfaces, EarlyView.
Volume changes of a solid‐state battery cell are separated into the individual contributions of anode and cathode. Simultaneously determining the “reaction volumes” of both electrodes requires a reference electrode with a pressure‐independent potential.
Mervyn Soans, Benedikt Huber, Marcel Drüschler, Dominic Bresser, Alberto Varzi, Christoffer Karlsson   +5 more
wiley   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Crystal structure of (E)-3-(2,4-dimethoxyphenyl)-1-(1-hydroxynaphthalen-2-yl)prop-2-en-1-one

Acta Crystallographica Section E, 2014
In the title compound, C21H18O4, the C=C bond of the central enone group adopts an E conformation. The dihedral angle formed by the benzene ring and the naphthalene ring system is 6.60 (2)°. The methoxy groups on the benzene ring are essentially coplanar
Dongsoo Koh
doaj   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source