Results 171 to 180 of about 49,484 (192)
The substrate‐solvent interactions play a major role in the modified OxFA process. Herein, the formation and stability of several reaction intermediates via acetalization depending on solvent composition and reaction conditions is investigated. The BioValCat (Enhanced Biomass Valorization by Engineering of Polyoxometalate Catalysts) project aims at ...
Leon Schidowski +4 more
wiley +1 more source
Through simultaneous molecular and supramolecular engineering, an atomically precise nanocluster Cu16 with ambient ultrastability and ultrabright luminescence is constructed. Cu16 employs a dual structural/luminescent channel mechanism to achieve orthogonal responsiveness to five external stimuli, demonstrating multidimensional signalling capability ...
Leon Li‐Min Zhang +7 more
wiley +1 more source
Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
wiley +1 more source
Abstract INTRODUCTION We examined obstructive sleep apnea (OSA) severity's association with Alzheimer's disease (AD) plasma biomarkers, independent or synergistic with cerebrospinal fluid (CSF) amyloid, and as a proof of concept, whether plasma amyloid beta (Aβ)42/Aβ40 with OSA severity improves detection of amyloidosis and tau pathology.
Omonigho Michael Bubu +25 more
wiley +1 more source
ABSTRACT Hypereosinophilia is uncommon in ASS and this presentation makes diagnosis more challenging. Anti‐PL12's role in the severity of ILD is controversial but its association with anti‐Ro52 seems to give a more serious disease phenotype. African ethnicity could be a negative prognostic factor, associated with lung disease severity.
Abeline Kapuczinski +4 more
wiley +1 more source
P450 goes peroxide: When one base just isn’t basic enough. Engineering a second basic residue into CYP199A4T252E boosts its peroxygenase activity but also makes it sensitive to H2O2. The double mutant F182R/T252E shows increased turnover before rapidly self‐destructing, revealing the fine balance between productive peroxide activation and oxidative ...
Pablo Velázquez García +3 more
wiley +1 more source
Utilization of Waste Materials Using the Müller–Kühne Process—A Life Cycle Inventory Study
This study presents a Life Cycle Inventory of the Müller–Kühne process (MKP), which converts gypsum waste into sulfuric acid and cement clinker. The MKP outperforms conventional cement production regarding material yield, though its specific energy demand is higher. Consequently, potentials for circular gypsum waste utilization are discussed.
Leon Kassner +4 more
wiley +1 more source
Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf +9 more
wiley +1 more source
MLDAS: Machine Learning Dynamic Algorithm Selection for Software‐Defined Networking Security
ABSTRACT Network security is a critical concern in the digital landscape of today, with users demanding secure browsing experiences and protection of their personal data. This study explores the dynamic integration of Machine Learning (ML) algorithms with Software‐Defined Networking (SDN) controllers to enhance network security through adaptive ...
Pablo Benlloch +3 more
wiley +1 more source
ABSTRACT Background Severe hypoglycemia is a major acute complication of type 1 diabetes (T1D) and is associated with increased morbidity, mortality, and impaired quality of life. Identifying individuals at the highest risk remains essential for optimising preventive strategies in real‐world practice.
Pablo Rodríguez de Vera Gómez +20 more
wiley +1 more source

