Results 31 to 40 of about 30,506 (294)

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

Estrategias interactivas e inclusivas para el desarrollo de habilidades cognitivas-motrices en el nivel de Educación Básica General

Gade: Revista Científica
El desarrollo de habilidades cognitivas-motrices en la Educación Básica General es fundamental para el crecimiento integral de los estudiantes. Estas estrategias promueven la participación activa, la colaboración y la adaptación de actividades que ...
Rosa Marlene Jumbo Obaco, Blanca Alicia Guiscasho Chicaiza, Marcela Paulina Samaniego Ojeda, Gustavo Joaquín Herrera Yaguana   +3 more
doaj   +1 more source

Beyond Nanoporosity: A CO2‐Conditioned Glassy Matrix Contributes to the Brittle‐to‐Ductile Transition of Nanocellular Polyetherimide

Advanced Materials, EarlyView.
The mechanical performance of nanocellular polyetherimide cannot be explained by nanoporosity alone. It is shown that CO2 saturation and desorption leave a distinct mechanical signature in the glassy matrix before foaming. This matrix contribution provides a new route to understand and optimize the brittle to ductile transition in nanocellular polymers.
Félix Lizalde‐Arroyo, Frederik Van Loock, Victoria Bernardo, Tuuli Peltola, René Bes, Alberto Tena, Miguel Ángel Rodríguez‐Pérez, Judith Martín‐de León   +7 more
wiley   +1 more source

Synthesis of Ladder and Flexible Polysulfonimides Directly From Anionic Monomers: Investigating Structure–Property Convergence in Succinonitrile–Polymer Electrolyte Blends

Angewandte Chemie, EarlyView.
Direct synthesis of sulfonimide‐based polymers of intrinsic microporosity enables comparison with compositionally similar flexible analogs. Incorporation of a common pore‐filling transport medium drives these fundamentally different polymer architectures toward similar bulk conductivity and mechanical properties while revealing distinct microscopic ion‐
Abraham Herzog‐Arbeitman, Pablo Leon, Benedikt S. Schreib, KyuJung Jun, Jurgis Ruza, Vanesa Munoz Perales, Yang Shao‐Horn, Rafael Gomez‐Bombarelli, Jeremiah A. Johnson   +8 more
wiley   +2 more sources

Napoleon and Ferdinand VII [PDF]

, 2011
Para Napoleón, Fernando era un enemigo por el mero hecho de ser un Borbón. Además, no sabía casi nada de él cuando los acontecimientos de El Escorial le revelaron que era cobarde y fácil de engañar.
Gérard Dufour, Dufour, Gérard
core   +1 more source

Unconventional Biexciton Dynamics in Superradiant Perovskite Quantum Dots Driven by Many‐Body Correlations

Advanced Materials, EarlyView.
Single‐particle spectroscopy and variational quantum Monte Carlo simulations reveal that strong many‐body correlations fundamentally alter biexciton radiative recombination in weakly confined CsPbBr3 quantum dots. Intra‐ and inter‐exciton correlations reverse the conventional lifetime hierarchy, yielding biexcitons with longer radiative lifetimes than ...
Chenglian Zhu, Jose L. Movilla, Petra Hoffmann, Ihor Cherniukh, Willem P. A. Verheijen, Leon G. Feld, Josep Planelles, Maryna I. Bodnarchuk, Simon C. Boehme, Juan I. Climente, Maksym V. Kovalenko, Gabriele Rainò   +11 more
wiley   +1 more source

„Gdyby opatrzność dała mi kilka lat czasu, bezsprzecznie uczyniłbym z Paryża stolicę świata”. Paryż w czasach Napoleona

Acta Universitatis Lodziensis: Folia Historica, 2021
Celem artykułu jest przeanalizowanie zmian, które zaszły w tkance miejskiej Paryża w czasach Napoleona (konsulatu i cesarstwa). Będą to więc budynki, pomniki wzniesione przez samego Bonapartego, które służyć miały chwale jego Wielkiej Armii, jego własnej,
Kamil Szadkowski
doaj   +1 more source

Single‐Particle FRET Probes Heterogeneity in the Ligand Shell of Colloidal Perovskite Quantum Dots

Advanced Materials, EarlyView.
Single‐particle, single‐molecule Förster resonance energy transfer turns dye‐tagged ligands into nanorulers for the otherwise elusive organic shell of CsPbBr3 quantum dots. Distance variations within individual particles reveal pronounced local heterogeneity, while changes in the surrounding ligand chemistry shift the average dye–surface separation ...
Leon G. Feld, Oleksandr Kolomiiets, Noah A. Shahin, Sebastian Sabisch, Amrutha Rajan, Gabriele Rainò, Maksym V. Kovalenko   +6 more
wiley   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

Advanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton, Carrillo Paola Gonzalez, Luay Almassalha, Wing Shun Li, Ruyi Gong, Nicolas Acosta, I Chae Ye, Jane Frederick, Christopher Hogg, Saira John, J. A. Gareth Williams, Rikkert J. Nap, Igal Szleifer, Vadim Backman   +13 more
wiley   +1 more source

“Those Were Glorious Times, Sir!” The Napoleonic Wars and the Image of the Partisan Figner in Dostoevsky’s Short Story “The Demobbed” [PDF]

Достоевский и мировая культура: Филологический журнал
This work is the first piece of research in the history of Dostoevsky studies dedicated to the early short story “The Demobbed,” which is part of the cycle Stories of an Experienced Man (From the Notes of an Unknown) (1848).
Nikolay N. Podosokorsky
doaj   +1 more source