Psoriatic onychodystrophy: indices for assessing the severity of psoriatic onychodystrophy (part 2)
Psoriatic onychodystrophy constitutes an important clinical manifestation of psoriasis and is characterised by multiple symptoms of damage to the nail bed and nail matrix.
A. V. Platonova +3 more
doaj +3 more sources
Background Psoriatic hard‐to‐treat areas (scalp, palmoplantar, genital and nails) are associated with lower efficacy, treatment discontinuation and impaired quality of life. Recent biotherapies offer a new perspective for their treatment.
Marc Perrussel, Bruno Sassolas
doaj +2 more sources
BACKGROUND: assessment instruments of nail psoriasis have been published in literature as means to standardize the previous subjective assessments of authors.
Maira Mitsue Mukai +4 more
doaj +2 more sources
The Relative Effects of Monotherapies for Psoriatic Nails: A Network Meta-Analysis Study. [PDF]
ABSTRACT Background Various treatments exist for nail psoriasis (NP). We determined the relative efficacy of various monotherapies through Bayesian network meta‐analyses (NMAs). Methods We systematically reviewed the literature to identify eligible studies which—within the patient, intervention, comparator, outcome (PICO) context—determined the impact ...
Gupta AK +3 more
europepmc +2 more sources
What Is the Diagnostic Capacity of Existing Severity Scoring Tools for Nail Psoriasis? [PDF]
ABSTRACT Background It is challenging to distinguish nail psoriasis (NP) from nonspecific nail changes, contributing to heterogeneity in clinical trials. Existing scoring tools for NP are currently used to assess severity after diagnosis is established.
Rikken ECC +5 more
europepmc +2 more sources
Advancement and independent validation of a deep learning-based tool for automated scoring of nail psoriasis severity using the modified nail psoriasis severity index [PDF]
ObjectiveTo improve and validate a convolutional neural network (CNN)-based model for the automated scoring of nail psoriasis severity using the modified Nail Psoriasis Severity Index (mNAPSI) with adequate accuracy across all severity classes and ...
Stephan Kemenes +30 more
doaj +2 more sources
Background: Nail involvement in psoriasis may be assessed clinically, ultrasonologically, and dermoscopically. The aim of this study was to assess the dermoscopic features of nails in psoriasis, compare them with clinical findings, and correlate them ...
Sandeep Arora +6 more
doaj +1 more source
Long-Term Impact of Guselkumab on Skin, Sexuality, and Perceived Stigmatization in Patients With Psoriasis in Routine Clinical Practice: Week 76 Effectiveness and Safety Results From the Prospective German Multicenter G-EPOSS Study. [PDF]
ABSTRACT Background G‐EPOSS is a prospective, non‐interventional, German multicenter study evaluating the effects of guselkumab, an interleukin‐23 inhibitor, in patients with moderate‐to‐severe plaque psoriasis in real‐world clinical practice. Objective To evaluate the effectiveness of guselkumab in psoriasis and its impact on quality of life (QoL ...
Gerdes S +11 more
europepmc +2 more sources
Nail psoriasis treated with pulsed dye laser [PDF]
: Nail changes are present in about 50% of psoriasis patients and tend to be refractory to conventional treatments. Pulsed dye laser has emerged as an alternative therapy.
Juliano Peruzzo +3 more
doaj +1 more source

