Results 121 to 130 of about 25,223 (258)

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

open access: yesAdvanced Science, Volume 12, Issue 26, July 10, 2025.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao   +7 more
wiley   +1 more source

Divergent input patterns to the central lateral amygdala play a duet in fear memory formation

open access: yesiScience
Summary: Somatostatin (SOM)-expressing neurons in the central lateral amygdala (CeL) are responsible for fear memory learning, but the circuit and molecular mechanisms underlying this biology remain elusive.
Jing-hua Gao   +9 more
doaj  

Status and Opportunities for Improvement in Pain Education in Europe: A European Pain Federation EFIC Multiple‐Methods Study

open access: yesEuropean Journal of Pain, Volume 29, Issue 6, July 2025.
ABSTRACT Background Pain is one of the most prevalent health issues in Europe, yet the quality of pain education for healthcare professionals remains unclear. This study assessed the status of undergraduate and postgraduate pain education for nurses, physicians, psychologists, and physiotherapists across Europe, identifying key strategies to enhance ...
Nathan Skidmore   +9 more
wiley   +1 more source

Barriers and Solutions to Implement HIV Pre‐Exposure Prophylaxis Program Among Key Populations in Iran: A Qualitative Study Using Causal Layered Analysis

open access: yesHealth Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aims HIV pre‐exposure prophylaxis (PrEP) has a crucial role in HIV prevention globally. Our study aimed to explore the approaches to address and overcome barriers to PrEP implementation among key populations in Iran. Methods In this multi‐stage qualitative study, first, we employed in‐depth interviews to identify possible ...
Hossein Moameri   +7 more
wiley   +1 more source

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