Results 131 to 140 of about 54,328 (276)
British Journal of Pharmacology, EarlyView.Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra +4 more
wiley +1 more source
Spontaneous and pharmacologically induced hypothermia protect mice against endotoxic shock
British Journal of Pharmacology, EarlyView.Background and Purpose Despite the well‐known occurrence of hypothermia during sepsis, its underlying biological nature and adaptive value remain debated. Experimental Approach Using indirect calorimetry, telemetry, thermal gradient studies and pharmacological studies, we examined the thermal and metabolic responses of mice treated with a shock ...
Arely Tinajero +7 more
wiley +1 more source
A Two-Layer Mathematical Modelling of Drug Delivery to Biological Tissues [PDF]
arXiv, 2016 Local drug delivery has received much recognition in recent years, yet it is still unpredictable how drug efficacy depends on physicochemical properties and delivery kinetics. The purpose of the current study is to provide a useful mathematical model for drug release from a drug delivery device and consecutive drug transport in biological tissue ...
arxiv
Unbearable Pain: India's Obligation to Ensure Palliative Care [PDF]
, 2009 This 102-page report found that many major cancer hospitals in India do not provide patients with morphine, despite the fact that more than 70 percent of their patients are incurable and likely to require pain treatment and palliative care.
core
Child &Family Social Work, EarlyView.ABSTRACT In Sweden, both maltreatment and behavioural problems are indicative of needs that motivate interventions from child welfare services (CWS). However, the likelihood of being referred to CWS can be influenced by other than indicative factors on individual, peer and school‐area levels.
Torbjörn Kalin
wiley +1 more source
Two Patterns of Narcotic Drug Addiction in the United States [PDF]
, 1965 John C. Ball
openalex +1 more source
From the Mountaintops: What the World Can Learn from Drug Policy Change in Switzerland [PDF]
, 2010 Reviews Switzerland's drug policy of policing, prevention, treatment, and harm reduction, including low-threshold methadone programs, needle exchanges, and safe injection rooms.
Csete, Joanne
core
Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging
Cell Proliferation, EarlyView.Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi +6 more
wiley +1 more source
Apprehending narcotic smugglers in Malta [PDF]
, 1992 This is an account of the experience of the radiological department in identifying heroin smugglers coming from the African continent in transit through Malta.
Zammit, Anthony
core
Drug and Alcohol Review, EarlyView.Abstract Introduction Various services and mutual‐aid groups, such as SMART Recovery, provide support for substance use rehabilitation in Singapore. Despite this, substance use remains a growing public health concern with a large treatment gap. This suggests potential barriers to accessing substance use treatment unique to Singapore's sociocultural ...
Wan Jie Tan +5 more
wiley +1 more source