Results 171 to 180 of about 3,781,173 (328)

A Sensitive and Comprehensive LC‐MS/MS Method for the Analysis of Hallucinogens, Synthetic Cathinones, and Synthetic Cannabinoids in Urine Samples

open access: yesJournal of Mass Spectrometry, Volume 60, Issue 10, October 2025.
ABSTRACT The laboratory analysis of new psychoactive substances and related drugs is crucial for accurate clinical and forensic diagnosis of poisonings. Given this, a new LC‐MS/MS method for analyzing hallucinogens, synthetic cathinones, and synthetic cannabinoids in urine was developed.
Bruno Pereira dos Santos   +6 more
wiley   +1 more source

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

open access: yesMedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan   +6 more
wiley   +1 more source

Simulated client study on the dispensing practices for narcotic and psychotropic medications in community drug outlets in Ethiopia. [PDF]

open access: yesDrugs Context
Zeleke TK   +12 more
europepmc   +1 more source

Performance of Large Language Models in Nursing Examinations: Comparative Analysis of ChatGPT‐3.5, ChatGPT‐4 and iFLYTEK Spark in China

open access: yesNursing Open, Volume 12, Issue 10, October 2025.
ABSTRACT Background While large language models (LLMs) have been widely utilised in nursing education, their performance in Chinese nursing examinations remains unexplored, particularly in the context of ChatGPT‐3.5, ChatGPT‐4 and iFLYTEK Spark. Purpose This study assessed the performance of ChatGPT‐3.5, ChatGPT‐4 and iFLYTEK Spark on the 2022 China ...
Peifang Li   +3 more
wiley   +1 more source

Benzodiazepine Use Among Individuals with Opioid Use Disorder: A Narrative Review. [PDF]

open access: yesSubst Abuse Rehabil
Liu Y   +6 more
europepmc   +1 more source

The mode of action of promethazine in potentiating narcotic drugs.

open access: yesBritish Journal of Anaesthesia, 1974
Narcotic Drugs, M. keeri-Szanto
semanticscholar   +1 more source

Identifying Pediatric Drug Safety Knowledge Gaps: An Integrated Approach Leveraging Real‐World Data, a Biomedical Knowledge Base, and Postmarketing Surveillance Data

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 667-676, October 2025.
ABSTRACT Background Drug safety has historically been understudied in pediatric populations, rendering them “therapeutic orphans.” Pediatric drug indications and dosages are often inferred by extrapolating safety, efficacy, and dosing data from adult studies, leading to widespread off‐label use.
Saurabh Rahurkar   +8 more
wiley   +1 more source

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