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A Comprehensive Review of Naringenin, a Promising Phytochemical with Therapeutic Potential
Journal of Microbiology and BiotechnologyDisorders, including cancer, metabolic disorders, and neurodegenerative diseases, can threaten human health; therefore, disease prevention is essential.
Jun Hong Shin, Seung Ho Shin
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Naringenin Derivatives as anti‐Atherogenic Agents.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Sangku, Lee +7 more
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Journal of Agricultural and Food Chemistry, 2022
Hyperuricemia characterized by high serum levels of uric acid (UA, >6.8 mg/dL) is regarded as a common chronic metabolic disease. When used as a food supplement, naringenin might have various pharmacological activities, including antioxidant, free ...
Bendong Yang +9 more
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Hyperuricemia characterized by high serum levels of uric acid (UA, >6.8 mg/dL) is regarded as a common chronic metabolic disease. When used as a food supplement, naringenin might have various pharmacological activities, including antioxidant, free ...
Bendong Yang +9 more
semanticscholar +1 more source
Targeting prostate cancer via therapeutic targeting of PIM-1 kinase by Naringenin and Quercetin.
International Journal of Biological MacromoleculesPIM-1 kinase belongs to the Ser/Thr kinases family, an attractive therapeutic target for prostate cancer. Here, we screened about 100 natural substances to find potential PIM-1 inhibitors.
A. Rathi +10 more
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Journal of Animal Physiology and Animal Nutrition, 2006
SummaryNaringenin is a bioactive flavanone involved in the inhibition of drug metabolism which exhibits antioxidant, anti‐inflammatory and anticancerogenic properties and which recently appeared to be a factor mitigating the hyperlipidaemic effects in rats and rabbits. In the performed experiment, the effect of naringenin, administered intragastrically
K, Szkudelska +3 more
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SummaryNaringenin is a bioactive flavanone involved in the inhibition of drug metabolism which exhibits antioxidant, anti‐inflammatory and anticancerogenic properties and which recently appeared to be a factor mitigating the hyperlipidaemic effects in rats and rabbits. In the performed experiment, the effect of naringenin, administered intragastrically
K, Szkudelska +3 more
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Naringenin and naringin in cardiovascular disease prevention: A preclinical review.
European Journal of Pharmacology, 2020Cardiovascular disease is an important cause for morbidity and mortality worldwide. Flavonoids, such as naringin, and naringenin are important natural phytochemicals in the treatment or prevention of various disorders such as obesity, cardiac diseases ...
Reza Heidary Moghaddam +5 more
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Naringenin attenuates cisplatin nephrotoxicity in rats
Life Sciences, 2005The effect of naringenin (NAR), a naturally occurring citrus flavanone, on the acute nephrotoxicity produced by cisplatin (7 mg/kg, i.v.) was investigated in the rat. Oral administration of NAR (20 mg/kg/day) for 10 days, starting 5 days before cisplatin single i.v. injection, produced significant protection of renal function. NAR reduced the extent of
Badary, Osama A. +3 more
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Sulfation of naringenin by Cunninghamella elegans
Phytochemistry, 2000A new flavonoid sulfate, naringenin-7-sulfate, was obtained by fermentation of naringenin using the fungus Cunninghamella elegans NRRL 1392 in 23% yield. Structural elucidation of the metabolite was achieved using EIMS, UV, IR, 1D and 2D NMR spectroscopy beside acid and enzyme hydrolyses.
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Naringenin reduces inflammatory pain in mice
Neuropharmacology, 2016Naringenin is a flavonoid widely consumed by humans that present anti-inflammatory activity and low toxicity. Recently, the analgesic effect of naringenin has been demonstrated in neuropathic pain models. Herein, we tested the analgesic effects of naringenin in several models of inflammatory pain. Mice received treatment with naringenin (16.7-150 mg/kg,
Felipe A. Pinho-Ribeiro +6 more
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Naringenin Nanoformulations for Neurodegenerative Diseases
Current Pharmaceutical Biotechnology: Glioblastoma (GBM) is a grade-IV astrocytoma, which is the most common and aggressive type of brain tumor, spreads rapidly and has a life-threatening catastrophic effect. GBM mostly occurs in adults with an average survival time of 15 to 18 months, and the overall mortality rate is 5%. Significant invasion and drug resistance activity cause the poor
Liza, Sahoo +2 more
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