Results 71 to 80 of about 318,222 (297)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Le DVD comme vecteur d’une culture du chapitre en contexte médiatique

open access: yesItinéraires, 2020
This article aims to outline a reflexion for a study of the use of chaptering in the field of DVD film publishing, a medium that is now in decline but that has introduced and popularized a radical change from the continuous viewing required before by VHS.
Alain Boillat
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Autobiografie d’infanzia. I "volti" in penombra custoditi dal Museo dell’Istituto degli Innocenti di Firenze

open access: yesStudi sulla Formazione
The history of the “spedale degli Innocenti” is famous throughout the world. It was the first orphanage founded in Europe in 1419 and its rooms contain the objects and stories of hundreds and hundreds of children cared for over the centuries.
Rossella Certini
doaj   +1 more source

Exploring the interplay of mode of discourse and proficiency level in ESL writing performance [PDF]

open access: yes, 2007
Recent theory in discourse and practice in rhetoric has suggested that writers require different skills and strategies when writing for different purposes, and in using different genres and modes (Kinneavy, 1972; Carrell and Connor, 1991) in writing. The
Heng, Chan Swee, Md. Rashid, Sabariah
core  

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

Accessibility of Vendor-Created Video Tutorials for People with Disabilities [PDF]

open access: yes, 2016
Many video, screencast, webinar, or interactive tutorials are created and provided by vendors for use by libraries to instruct users in database searching.
Oud, Joanne
core   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett   +5 more
wiley   +1 more source

“ALEKSANDR SEMENOVICH ROKK”: CHIEF COMMANDER OF THE WORKERS’ AND PEASANTS’ RED ARMY S.S. KAMENEV AND HIS SURROUNDINGS IN THE NOVEL BY M. BULGAKOV “THE FATAL EGGS”

open access: yesНеофилология, 2018
The historical and political prototypes are the material for the creation of bright and memorable images in the novel by M.A. Bulgakov “Fatal eggs” are described: A.S. Rokk (chief commander of the Workers' And Peasants' Red Army S.S.
Vladimir Viktorovich Kolchanov
doaj   +1 more source

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