Results 41 to 50 of about 1,321,283 (297)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Coyote\u27s Tale on the Old Oregon Trail: Challenging Cultural Memory through Narrative at the Tamástslikt Cultural Institute [PDF]

open access: yes, 2005
This essay examines the oppositional narratives presented in a Native American museum in order to explore the efficacy of narrative as both a strategy for resistance to hegemonic narratives of the settling of the West and a medium for sharing culture ...
Miller, Jackson B.
core   +1 more source

Narratives of change

open access: yesThe South Asianist, 2020
Adaptation is becoming increasingly significant for public policy and practice in dealing with climate change-related risks and achieving sustainable development. Consequently, the exploration of different ways of assisting successful adaptation has brought under scrutiny the different lifestyles of communities all around the world.
Per Becker, Phu Doma Lama
openaire   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Phenomenological-narrative contributions to understand the narrative strategies that shape the autobiographical account throughout different moments of the therapeutic process

open access: yesResearch in Psychotherapy, 2018
Different studies suggest that the strategies and narrative styles that people use to construct their autobiographical accounts have repercussions on their self-organization, as well as on their identity experience and their conception of the world ...
Dante Gabriel Duero   +1 more
doaj   +1 more source

Drug Misuse: Taking a Narrative Approach as a Means of Exploring ‘Self-Change’ [PDF]

open access: yes, 2002
In this paper I explore the personal narrative of Jennifer; a woman who for the past ten years had been using ‘hard’ drugs. When interviewed Jennifer had been ‘sentenced’ to take part in an enforced treatment programme which aimed to facilitate ‘self ...
Horrocks, Christine
core  

Warfare, Taxation, and Political Change: Evidence from the Italian Risorgimento [PDF]

open access: yes, 2011
We examine the relationships between warfare, taxation, and political change in the context of the political unification of the Italian peninsula. Using a comprehensive new database, we argue that external and internal threat environments had significant
Dincecco, Mark   +2 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Giving Sense to Change Leadership: Towards a Narrative-Based Process Model

open access: yesEconomic and Business Review, 2023
Introduction: Recent studies on change agency and organizational change failure have significantly broadened the organizational behavior perspective on individual change experiences, however, the underlying mechanism for change leaders’ influential ...
Antonio Sadarić, Miha Škerlavaj
doaj   +1 more source

From area-based initiatives to strategic partnerships: have we lost the meaning of regeneration? [PDF]

open access: yes, 2012
For forty years area-based initiatives (ABIs) were the primary tool used by UK governments to tackle problems of concentrated deprivation and dereliction.
Matthews, Peter
core   +2 more sources

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