Results 181 to 190 of about 1,142,916 (305)

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

A Hybrid Type II Hub-and-Spoke Model Evaluation Framework in the Commonwealth Partnerships for Antimicrobial Stewardship Programme-A Study Protocol. [PDF]

Antibiotics (Basel)
Iqbal A, Gülpinar G, Brandish C, Nabiryo M, Garraghan F, Rutter V.   +5 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Narrative foreclosure among patients with chronic diseases: a scoping review. [PDF]

Front Public Health
Xu Z, Cui S, Hu N, Sun M, Huang X, Chen K, Wang S, Jiang Y.   +7 more
europepmc   +1 more source

Single‐Crystalline Borate Covalent Organic Frameworks for Solid‐State Lithium Metal Batteries

Advanced Science, EarlyView.
Advancing lithium metal batteries demands novel solid‐state electrolytes. Covalent organic frameworks (COFs) offer high ion conduction via porosity and functional groups. We synthesized single‐crystalline 3D borate COF with 8.1 mS cm−1 conductivity and 0.98 Li+ transference.
Ye Tian, Xiaolong Cheng, Lei Cheng, Yide Chang, Jixin Wu, Muhua Gu, Ki‐Taek Bang, Rui Wang, Ran Tao, Yufeng Wang, Soonyong So, Yanming Wang, Yoonseob Kim   +12 more
wiley   +1 more source

Physical activity interventions for older adults - an overview of systematic reviews. [PDF]

BMC Public Health
Canneaux J, Sharpe RA, Orr N, Smith JR, Bethel A, Phoenix C, Goodwin VA, Lang I, Garside R.   +8 more
europepmc   +1 more source

An Advanced High‐Performance Ultrafast Ammonium‐Ion Aqueous Battery Based on Dual‐Metal Redox Open Framework Molecular Magnet

Advanced Science, EarlyView.
The Prussian Blue Analogue molecular magnet KMnFeHCF is demonstrated as a high‐performance cathode for ultra‐fast aqueous ammonium‐ion batteries. A full cell using KMnFeHCF and graphite delivers ~71 mAh g−1 at 1.25 A g−1 and ~51 mAh g−1 at 2.2 A g−1, retaining 50% capacity after 1850 cycles. Its scalability, cycling stability, and low cost offer strong
Nilasha Maiti, Pramod Bhatt, Manoj K Sharma, Sher Singh Meena, Mayuresh D Mukadam, Soumen Samanta   +5 more
wiley   +1 more source

Digital technology, emotions, and social relationships in dementia care: A narrative review. [PDF]

Digit Health
Persson M, Bivall AC, Thunman E.
europepmc   +1 more source

Photocatalytically Activated Cu‐N1S3 Single‐Atom Nanozyme: Enhancing Enzyme Activities and Antibacterial Synergy for Highly Efficient Fruit Preservation

Advanced Science, EarlyView.
This study presents S‐coordinated Cu single‐atom nanozymes (Cu/CNS) fabricated via mild photocatalytic self‐assembly strategy. The nanozyme exhibits exceptional multi‐enzyme activity and near‐perfect antimicrobial efficacy. Incorporated into chitosan‐gelatin film, it enables pH‐responsive, broad‐spectrum fruit preservation, more than doubling the shelf‐
Chuanlong Men, Chenchen Wu, Lei Wang, Shengjie Gao, Yu Mao, Wei Liu, Changhong Liu, Lei Zheng   +7 more
wiley   +1 more source

Research on the influencing factors of sustainable fundraising in internet medical crowdfunding: based on dramaturgical theory. [PDF]

Front Public Health
Huang Z, Han Z.
europepmc   +1 more source