Results 91 to 100 of about 114,279 (249)

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

open access: yesAdvanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng   +20 more
wiley   +1 more source

Changing midlife tropes: A transcendence into epiphany

open access: yesThe Indo-Pacific Journal of Phenomenology
Midlife is often stereotyped as a time of turbulence, angst and chaos, marked by inappropriate behaviours, broken marriages, infidelity and destructive changes. However, this article aims to challenge these stereotypes and present a different perspective.
Louisa Niehaus, Maria Papaikonomou
doaj   +1 more source

Electroconvulsive Therapy and Hyperventilation: A Narrative Review

open access: yesLife
Electroconvulsive therapy (ECT) is a non-pharmacological biological treatment method used to treat major depression, bipolar disorder, schizophrenia, catatonia, and some other psychiatric conditions. Despite its high effectiveness, it is often used when other methods, such as pharmacotherapy and psychotherapy, fail to improve treatment outcomes.
Joanna Smolarczyk   +7 more
openaire   +3 more sources

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

open access: yesAdvanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin   +13 more
wiley   +1 more source

Towards a decentred, politically influential, accountable and yet uncertain practice

open access: yesInternational Journal of Narrative Therapy and Community Work
A “decentred” therapeutic stance is often seen as one of the hallmarks of narrative practice. But it isn’t always well understood and is interpreted differently by different practitioners.
Kelsi Semeschuk
doaj   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

open access: yesAdvanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg   +16 more
wiley   +1 more source

It takes a village to raise a child: Community healing for traumatised children and young people with the “Here You, Hear Me” card game

open access: yesInternational Journal of Narrative Therapy and Community Work
This video highlights the crucial role of community participation in supporting traumatised children and young people. Our project focuses on co-creation and community healing, beginning with the collaborative design of a card game developed in ...
Ka Fai Kwong, Sau Mui Wong
doaj   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

open access: yesAdvanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun   +13 more
wiley   +1 more source

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