Evaluating a virtual paediatric adverse drug reaction clinic
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck +2 more
wiley +1 more source
Narrative exposure therapy in early intervention in psychosis services (NETp): protocol of a multi-site feasibility randomised controlled trial study . [PDF]
Fornells-Ambrojo M +8 more
europepmc +1 more source
Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood +6 more
wiley +1 more source
Written Exposure Therapy as Transformative, Scalable Care for Posttraumatic Stress Disorder. [PDF]
Sage CM.
europepmc +1 more source
This study provides the first open‐source tool to implement the complete TEN‐SPIDERS framework in linked datasets for the determination of the PDC for medication adherence. The TEN‐SPIDERS tool enables transparent, reproducible medication adherence research through automated reporting of all calculation parameters and flexible customization options ...
Adam C. Livori +8 more
wiley +1 more source
Correction: Collagen, Curcumin, and Glutathione to Enhance Dermal Health with Declining Estrogen Levels in Aging Women-A Narrative Review. [PDF]
Arbex P, Lephart ED.
europepmc +1 more source
Applying machine learning to pharmacovigilance data: A proof‐of‐concept study
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus +6 more
wiley +1 more source
Psychedelic-Assisted Interventions in Palliative Care: A Narrative Overview and Critical Evaluation. [PDF]
Soares DA, Campolina AG.
europepmc +1 more source
Indications for Dual Antiplatelet Therapy in Coil-Only Treatment of Ruptured Intracranial Aneurysms: A Narrative Review. [PDF]
Sowa M, Sowa J.
europepmc +1 more source
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili +6 more
wiley +1 more source

