Results 131 to 140 of about 2,438,339 (329)

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Tolerability of Concomitant Administration of Mometasone Furoate and Oxymetazoline Nasal Sprays Administered Once Daily vs Oxymetazoline Twice Daily, Mometasone Furoate Once Daily, and Placebo in the Treatment of Subjects With Seasonal Allergic Rhinitis [PDF]

, 2010
Anjuli Nayak, Bruce M. Prenner, D. Gates, Tulin Shekar, Ariel Teper   +4 more
openalex   +1 more source

Comparative Serum and Brain Pharmacokinetics of Quercetin after Oral and Nasal Administration to Rats as Lyophilized Complexes with β-Cyclodextrin Derivatives and Their Blends with Mannitol/Lecithin Microparticles

, 2023
Konstantina Manta, Paraskevi Papakyriakopoulou, Anna Nikolidaki, Evangelos Balafas, Nikolaos Kostomitsopoulos, Sabrina Banella, Gaia Colombo, Georgia Valsami   +7 more
openalex   +1 more source

The effect of intra-nasal insulin & growth factor-rich serum administration on memory and behavior defects induced by icv-STZ rat model and correlation analysis of hippocampus oxidative-nitrosative state with spatial memory and anxiogenic behavior [PDF]

, 2023
Mahdi Khorsand Ghaffari, Ali Rafati, Narges Karbalaei, Masoud Haghani, Marzieh Nemati, Niloofar Sefati, Mohammad Reza Namavar   +6 more
openalex   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Nasal Administration of bFGF-Loaded Nanoliposomes Attenuates Neuronal Injury and Cognitive Deficits in Mice with Vascular Dementia Induced by Repeated Cerebral Ischemia‒Reperfusion

International Journal of Nanomedicine
Ming Zhang,1 Shuai-shuai Huang,1 Wen-yue He,1 Wei-juan Cao,2 Min-yi Sun,1 Ning-wei Zhu2 1Department of Pharmacy, Ningbo Yinzhou NO.2 Hospital, Ningbo, Zhejiang, 315100, People’s Republic of China; 2Department of Pharmacy, Zhejiang Pharmaceutical ...
Zhang M, Huang SS, He WY, Cao WJ, Sun MY, Zhu NW   +5 more
doaj  

Advancements in nasal drug delivery system of natural products

Frontiers in Pharmacology
BackgroundNasal drug delivery offers a non-invasive route with rapid absorption and the ability to bypass first-pass metabolism, making it promising for central nervous system (CNS) disorders, nasal diseases such as allergic rhinitis, and other chronic ...
Yenna Hsu, Yenna Hsu, Jiajing Yang, Jiajing Yang, Miaoyang Cao, Miaoyang Cao, Ting Xu, Ting Xu, Jia He, Jia He, Huarong Hong, Huarong Hong, Luyun Jiang, Luyun Jiang, Shunlin Peng, Shunlin Peng, Peizheng Xiong, Peizheng Xiong   +17 more
doaj   +1 more source

Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]

, 2009
The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon, Barranco, Wade T, Corry, David B, Dong, Chen, Goswami, Sangeeta, Greenlee, Kendra J, Kheradmand, Farrah, Polikepahad, Sumanth, Redding, David, Seryshev, Alexander, Shan, Ming, Singh, Bhupinder, Song, Li-zhen, Sur, Sanjiv, Woodruff, Prescott   +14 more
core  

Improvement of functional neurological disorder after administration of esketamine nasal spray: a case report [PDF]

, 2021
Júlia Vendrell-Serres, Óscar Soto-Angona, Amanda Rodríguez‐Urrutia, Gara Arteaga-Henríquez, Josep Antoni Ramos‐Quiroga   +4 more
openalex   +1 more source