Results 291 to 300 of about 2,438,339 (329)

Nasal Administration: A Tool for Tomorrow's Systemic Administration of Drugs

Drug Development and Industrial Pharmacy, 1993
AbstractBy its anatomy and physiology, due to the great amount of air treated there, the nasal route represents a very interesting possibility for the administration of products degraded in the gastro-intestinal tract or inhibited by the first hepatic pass.
Dominique Duchěne, Gilles Ponchel
openaire   +1 more source

Nasal Administration of Granisetron to Rats

Journal of Korean Pharmaceutical Sciences, 2006
Granisetron is a selective 5-HT3 receptor antagonist that is used therapeutically for the prevention of vomiting and nausea associated with emetogenic cancer chemotherapy. Although this drug is commercially available for intravenous and oral dosage, there is a need for intranasal delivery formulations in specific patient populations in which the use of
openaire   +1 more source

Nasal Administration

Menopause, 2003
Saranya Wattanakumtornkul, Anil Pinto, Daniel B. Williams   +2 more
openaire   +2 more sources

Swimming short fibrous nasal drops achieving intraventricular administration

Science Bulletin
Adequate drug delivery across the blood-brain barrier (BBB) is a critical factor in treating central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of the nasal cavity, this study is the first to develop swimming short fibrous nasal drops that can directly target the nasal mucosa and swim in the nasal cavity, which can
Juan, Wang, Qiuyun, Wang, Yifei, Fu, Min, Lu, Liang, Chen, Zhiheng, Liu, Xiaohan, Fu, Xiyu, Du, Buwei, Yu, Han, Lu, Wenguo, Cui   +10 more
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Nasal administration of naloxone for detection of opiate dependence

Journal of Psychiatric Research, 1992
In clinical trials, nasally applied naloxone was used to identify opiate dependence in humans for the first time. Withdrawal distress was recorded, and pupillary response, pulse rate and blood pressure measured. A significant increase in withdrawal distress and pupillary dilation was observed after nasal administration of 1mg (1mg/400 microliters ...
N, Loimer, P, Hofmann, H R, Chaudhry
openaire   +2 more sources

Nasal mucosa inflammation induced by oxygen administration in humans

Acta Anaesthesiologica Scandinavica, 1997
Background: The effect of oxygen toxicity in human airways is still poorly documented. We prospectively evaluated the inflammatory reaction induced by nasal oxygen exposure in an experimental setting.Methods: Healthy subjects without nasal symptoms were exposed to high FIO2 during 5 h. Oxygen was delivered from a tank at a flow of 41/min to one nostril
G, Capellier, Z, Zhang, M F, Maheu, H, Pointet, E, Racadot, B, Kantelip, J, Regnard, F, Barale   +7 more
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[Stomach rupture after nasal oxygen administration].

Annales francaises d'anesthesie et de reanimation, 2004
We report a case of a spontaneous rupture of a normal stomach after therapeutic oxygen administration. In this case, early treatment precluded the need for a laparotomy. This rare complication highlights the importance of the right positioning of a nasal catheter and leads us to question its role compared to other means of oxygen delivery (nasal ...
M, Adam, M A, Boughaba, V, Kuoch, F, Blot, E, Desruennes   +4 more
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Desmopressin Dry Powder for Nasal Administration

2007
Purpose: To produce a dry powder formulation for the antidiuretic cyclic peptide desmopressin acetate (DDAVP) as an alternative to conventional liquid nasal formulations.
COLOMBO, Gaia, P. RUSSO, F. SONVICO, E. HESSE, FERRARO, Luca Nicola, BORTOLOTTI, Fabrizio, P. COLOMBO   +6 more
openaire   +2 more sources

Nasal Administration of Cationic Nanoemulsions as CD73-siRNA Delivery System for Glioblastoma Treatment: a New Therapeutical Approach

Molecular Neurobiology, 2019
J. Azambuja, R. Schuh, L. R. Michels, N. Gelsleichter, L. Beckenkamp, I. Iser, G. Lenz, F. H. D. Oliveira, G. Venturin, S. Greggio, J. daCosta, M. Wink, Jean Sévigny, M. Stefani, A. Battastini, H. Teixeira, E. Braganhol   +16 more
semanticscholar   +1 more source

Improving hypoglycemic effect of insulin via the nasal administration of deep eutectic solvents.

International journal of pharmaceutics, 2019
Yang Li, Xiying Wu, Quangang Zhu, Zhongjian Chen, Yi Lu, Jianping Qi, Wei Wu   +6 more
semanticscholar   +1 more source