Results 91 to 100 of about 182,368 (356)

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

open access: yesAdvanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan   +9 more
wiley   +1 more source

Relational Reasoning Network (RRN) for Anatomical Landmarking

open access: yes, 2019
Accurately identifying anatomical landmarks is a crucial step in deformation analysis and surgical planning for craniomaxillofacial (CMF) bones. Available methods require segmentation of the object of interest for precise landmarking.
Bagci, Ulas   +7 more
core  

Surgical reconstruction of a frontonasal orbital-etmoidal fracture [PDF]

open access: yes, 2009
Frontal sinus fractures are originated from high intensity accidents, including automobile accidents, altercations, sports accidents and falls. Normally, they are associated with fractures of the middle third of the face, including maxillary, nasal ...
Cláudio Maldonado Pastori   +4 more
core  

A New Genus of Miniaturized and Pug-Nosed Gecko from South America (Sphaerodactylidae: Gekkota) [PDF]

open access: yes, 2011
Sphaerodactyl geckos comprise five genera distributed across Central and South America and the Caribbean. We estimated phylogenetic relationships among sphaerodactyl genera using both separate and combined analyses of seven nuclear genes.
Bauer, Aaron M.   +4 more
core   +2 more sources

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan   +9 more
wiley   +1 more source

Multiple anti-predator mechanisms in the red-spotted Argentina Frog (Amphibia: Hylidae) [PDF]

open access: yes, 2017
Anurans employ a wide variety of anti-predator mechanisms to defend themselves. In casque-headed hylids, defence is thought to be a complex combination of several anti-predator mechanisms. However, the defence traits of only a few species are known; some
Alcalde, Leandro   +6 more
core   +2 more sources

A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics

open access: yesAdvanced Science, EarlyView.
Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie   +8 more
wiley   +1 more source

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

open access: yesAdvanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee   +28 more
wiley   +1 more source

Absent nasal bone [PDF]

open access: yesAmerican Journal of Obstetrics and Gynecology, 2019
Beryl R. Benacerraf   +2 more
openaire   +3 more sources

A Soft Wearable Modular Assistive Glove Based on Novel Miniature Foldable Pouch Motor Unit

open access: yesAdvanced Intelligent Systems, EarlyView.
This study presents a miniature foldable pouch motor unit and a novel fabrication process that enables the production of the actuator using a simple full heat‐sealing approach. The actuator maintains excellent performance under low‐pressure conditions.
Tianyu Zhang   +3 more
wiley   +1 more source

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