Results 191 to 200 of about 1,951,889 (321)

Efficacy of Eribulin Monotherapy in Patients With Unresectable and/or Metastatic Adenoid Cystic Carcinoma Receiving Platinum‐Based Therapy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is the second most common and treatment‐resistant salivary gland carcinoma (SGC). Although platinum‐based therapies are effective, the efficacy of eribulin, a microtubule inhibitor with an 18% response rate in a Phase II trial involving recurrent/metastatic SGC, in patients with advanced ACC after ...
Tomomi Sanomachi   +16 more
wiley   +1 more source

Safety and Oncologic Outcomes of Endoscopic Endonasal Transcribriform Approach for Locally Advanced Sinonasal Malignancies

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction The past two decades have seen a paradigm shift in the surgical treatment of sinonasal malignancies, moving from traditional open approaches to minimally invasive endoscopic techniques. Technological advancements have enabled the use of the endoscopic endonasal transcribriform approach (EETA) for tumors involving the anterior ...
Michel Khalaf   +11 more
wiley   +1 more source

A Systematic Review of the Clinical Impact of Implementing Artificial Intelligence in Upper Aerodigestive Tract Endoscopy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Endoscopy is essential in upper aerodigestive tract (UADT) examination, particularly in the early detection of laryngopharyngeal lesions. However, UADT endoscopy remains operator‐dependent and lacks standardized quality metrics. Recent advancements in artificial intelligence (AI) have generated interest in applications within UADT ...
Celine M. L. H. Wilmes   +4 more
wiley   +1 more source

Hemangioma of the Nasal Bone

open access: yesPractica Oto-Rhino-Laryngologica, 1974
Yusuke Shimizu, Satoru Kitano
openaire   +2 more sources

Mechanisms of enhancer‐driven oncogene activation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend   +2 more
wiley   +1 more source

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