Results 271 to 280 of about 182,368 (356)

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Reconstruction of Total Nasal Defect Including Skin, Bone, and Lining, Using a Single Free Radial Forearm Osteocutaneous Perforator Flap

, 2012
Masaki Fujioka, Kenji Hayashida, Chikako Murakami, Yasushi Koga   +3 more
openalex   +1 more source

Postnatal determinants of testicular germ cell tumor by histological subtypes: The EPSAM1 and EPSAM2 studies

International Journal of Cancer, EarlyView.
What's New? While several nongenetic risk factors are linked to testicular germ‐cell tumors (TGCTs), the influence of environmental and hormonal factors remains unclear. This study evaluated the role of postnatal exposures in the etiology of TGCT using data from the ongoing EPSAM case–control investigation in Italy.
Mauro Cioffi, Giovenale Moirano, Elena Isaevska, Valentina Fiano, Massimo Di Maio, Patrizia Lista, Ilaria Depetris, Andrea Zitella, Pietro Quaglino, Lorenzo Richiardi, Maja Popovic   +10 more
wiley   +1 more source

[Imaging diagnosis of the temporal bone and nasal-paranasal sinuses using cone-beam CT].

, 2012
Yo Ogawa
openalex   +2 more sources

Incidence and temporal trends of depression and anxiety following cancer diagnosis in Japan: Insights from the LIFE study

International Journal of Cancer, EarlyView.
What's New? Depression and anxiety are common but often under‐recognized among cancer patients. Using claims data from 14 municipalities in Japan, this study clarified the incidence and temporal trends of these conditions following cancer diagnosis over a 24‐month follow‐up period.
Kengo Kawaguchi, Megumi Maeda, Fumiko Murata, Makoto Endo, Yasuharu Nakashima, Haruhisa Fukuda   +5 more
wiley   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Quality of life of patients with nasal bone fracture after closed reduction. [PDF]

Arch Craniofac Surg, 2020
Park YJ, Do GC, Kwon GH, Ryu WS, Lee KS, Kim NG.   +5 more
europepmc   +1 more source

Frontonasal Fold Thickness-to-Nasal Bone Length Ratio as a Prenatal Sonographic Marker for Trisomy 21 in a Low-Risk Population

, 2013
Rubén González Crespo, Sócrates Aedo, V. Dezerega, Waldo Sepúlveda   +3 more
openalex   +1 more source

Nasal bone fracture

, 2019
openaire   +1 more source

Distribution and Antimicrobial Resistance of Pathogenic Bacteria in Patients With Sternal Osteomyelitis

iLABMED, EarlyView.
This study conducted a retrospective analysis of microbiological culture results and antimicrobial resistance patterns in patients with sternal osteomyelitis at a tertiary medical center. The primary pathogens causing sternal osteomyelitis were gram‐positive bacteria. Infections with multidrug‐resistant organisms were also relatively common among these
Yumin Yang, Manhui Zhang, Yue Pan, Lihua Qi, Zhigang Wang, Xian Xia   +5 more
wiley   +1 more source