Results 111 to 120 of about 18,068,689 (248)

Scalable Crackle‐Lithography for Multifunctional Enclosed Plastic Nanofluidic Devices

open access: yesAdvanced Science, EarlyView.
Crackle‐lithography enables scalable fabrication of enclosed plastic‐substrate‐based nanofluidic devices with interconnected nanochannels that enable molecular transport, optical interrogation, confined electroless copper deposition, and ionic memristive behavior.
Tirumala Rao Dumpala   +8 more
wiley   +1 more source

Nasal High-Flow Therapy in Postextubation Respiratory Failure

open access: yes, 2019
Nasal high-flow therapy (NHF) is an emerging respiratory therapy that has been gaining traction in acute care settings throughout the world. Critically eyed at the beginning, the benefit of NHF therapy has been demonstrated in clinical practice.
Maggiore S. M., Battilana M., Petrini F.
core  

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

MOESM1 of High-flow nasal cannula therapy: clinical practice in intensive care units

open access: yes, 2019
Additional file 1.
Sinad Hobeika (7346489)   +11 more
core   +1 more source

Nasal high flow, but not supplemental O2, reduces peripheral vascular sympathetic activity during sleep in COPD patients

open access: yesInternational Journal of COPD, 2018
K Fricke,1,2 H Schneider,1 P Biselli,1,3 NN Hansel,1 ZG Zhang,1,4 MO Sowho,1 L Grote1,5,6 1Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA; 2Department for Pulmonary, Sleep ...
Fricke K   +6 more
doaj  

Comparison of Hypoxia Incidence between High Flow Nasal Cannula and Simple Nasal Cannula during Deep Sedation for Upper Gastrointestinal Endoscopy: An Observational Study

open access: yesJournal of Nepal Medical Association
Introduction: Hypoxia is a common complication during upper gastrointestinal endoscopyunder deep sedation. While simple nasal cannulas are commonly used for oxygen delivery, high-flow nasal cannulas (HFNC) provide higher oxygen levels, generate positive
Anuj Jung Karki   +4 more
doaj   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

open access: yesAdvanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling   +18 more
wiley   +1 more source

Maintaining Oxygenation Successfully with High Flow Nasal Cannula during Diagnostic Bronchoscopy on a Postoperative Lung Transplant Patient in the Intensive Care

open access: yesCase Reports in Critical Care, 2014
Bronchoscopy is an important diagnostic and therapeutic intervention for a variety of patients displaying pulmonary pathology. The heterogeneity of the patients undergoing bronchoscopy affords a challenge for providing minimal and safe respiratory ...
Sara Diab, John F. Fraser
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

open access: yesAdvanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu   +14 more
wiley   +1 more source

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