Results 171 to 180 of about 74,961 (259)

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Paradoxical psoriasiform dermatitis involving the nasal mucosa in the setting of infliximab for inflammatory bowel disease. [PDF]

JAAD Case Rep
Jacob-George S, Yim K, Deng A, Nutan FNU, Levin NA.   +4 more
europepmc   +1 more source

Nocturnal awakening secondary to pain in sleep‐related painful erection: A case report and literature review

Sleep Research, EarlyView.
Abstract A 41‐year‐old male patient presented with a 13‐year history of recurrent nocturnal penile pain associated with erections during sleep. Over the course of his illness, the patient attended outpatient clinics on 298 occasions and was hospitalized three times. The primary symptom reported was erectile pain occurring during sleep.
Liping Zhang, Jinxiang Cheng, Jiaxiu He, Rui Guo, Changjun Su, Xianchao Zhao   +5 more
wiley   +1 more source

Transcriptomic Profiles of the Nasal Mucosa Following Birch Pollen Provocation Differ Between Birch Pollen-Allergic and Non-Allergic Individuals. [PDF]

Allergy
Sudharson S, Eckl-Dorna J, Meshcheryakova A, Basílio J, Derdak S, Kalic T, Lengger N, Schweitzer N, Mechtcheriakova D, Breiteneder H, Hafner C.   +10 more
europepmc   +1 more source

Epithelial Barrier in the Nasal Mucosa, Related Risk Factors and Diseases.

Int Arch Allergy Immunol, 2023
Zhang R, Zhang L, Li P, Pang K, Liu H, Tian L.   +5 more
europepmc   +1 more source

Predictability of obstructive sleep apnea with a somesthetic screening score: Development and preliminary validation in a prospective study

Sleep Research, EarlyView.
This prospective study developed a two‐step clinical scoring system for obstructive sleep apnea (OSA) screening based on patients’ somesthetic perception of oropharyngeal airflow. The Intermediate Score (IS ≥ 7.5) achieved 73% sensitivity and 77% specificity (AUC = 0.7754; OR = 8.96).
Cédric Garcion, Alain Piron, Alain Lacroix, Bassam Chakar, Christophe Di Piazza   +4 more
wiley   +1 more source

Inflammation of the nasal mucosa is associated with susceptibility to experimental pneumococcal challenge in older adults. [PDF]

Mucosal Immunol
Urban BC, Gonçalves ANA, Loukov D, Passos FM, Reiné J, Gonzalez-Dias P, Solórzano C, Mitsi E, Nikolaou E, O'Connor D, Collins AM, Adler H, Pollard A, Rylance J, Gordon SB, Jochems SP, Nakaya HI, Ferreira DM.   +17 more
europepmc   +1 more source

Applications of chitosan derivatives as adjuvants for nanoparticle‐based vaccines: A comprehensive review

Smart Molecules, EarlyView.
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta, Susanta Paul, Swarupananda Mukherjee, Nilanjan Sarkar, Arvind Kumar, Amrita Chakraborty, Anannya Bose, Atanu Hazra, Mainak Chakraborty   +8 more
wiley   +1 more source

The function and mechanism of Human nasal mucosa-derived mesenchymal stem cells in allergic rhinitis in mice. [PDF]

Inflamm Res
Liu Y, Liu S, Meng L, Fang L, Yu J, Yue J, Li T, Tu Y, Jiang T, Yu P, Wan YZ, Lu Y, Shi L.   +12 more
europepmc   +1 more source

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots

Environmental Toxicology, EarlyView.
ABSTRACT The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalian toxicity.
Yudum Yeltekin Uğur, Rahsan Ilikci‐Sagkan, Recep Liman   +2 more
wiley   +1 more source