Results 211 to 220 of about 346,071 (293)

Inflammation of the nasal mucosa is associated with susceptibility to experimental pneumococcal challenge in older adults. [PDF]

Mucosal Immunol
Urban BC, Gonçalves ANA, Loukov D, Passos FM, Reiné J, Gonzalez-Dias P, Solórzano C, Mitsi E, Nikolaou E, O'Connor D, Collins AM, Adler H, Pollard A, Rylance J, Gordon SB, Jochems SP, Nakaya HI, Ferreira DM.   +17 more
europepmc   +1 more source

Epithelial Barrier in the Nasal Mucosa, Related Risk Factors and Diseases.

Int Arch Allergy Immunol, 2023
Zhang R, Zhang L, Li P, Pang K, Liu H, Tian L.   +5 more
europepmc   +1 more source

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell‐cycle, MAPK, and PI3K pathways

The Journal of Pathology, EarlyView.
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti, Martina Brigida Romanello, Luca Agnelli, Matteo Orlandi, Luca Bertoli, Sara Picinoli, Irene Pezzali, Giulio Eugenio Mandelli, Daniela Medicina, Giovanni Ribaudo, Adele Busico, Elena Conca, Vilma Pellegrini, Piera Balzarini, Daniele Gallucci, Anna Di Matteo, Davide Lombardi, Claudia Ghigna, Giancarlo Pruneri, Alessandra Gianoncelli, Marzia Rossato, William Vermi   +21 more
wiley   +1 more source

Transcriptomic Profiles of the Nasal Mucosa Following Birch Pollen Provocation Differ Between Birch Pollen-Allergic and Non-Allergic Individuals. [PDF]

Allergy
Sudharson S, Eckl-Dorna J, Meshcheryakova A, Basílio J, Derdak S, Kalic T, Lengger N, Schweitzer N, Mechtcheriakova D, Breiteneder H, Hafner C.   +10 more
europepmc   +1 more source

Exploring the causes and impact of pediatric complicated mild traumatic brain injuries

PM&R, EarlyView.
Abstract Background Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children, with mild TBI (mTBI) accounting for approximately 80% of cases. Complicated mTBI (c‐mTBI) is characterized by radiographic evidence of intracranial abnormalities and/or skull fractures.
Andrew D. Kramer, Arianna B. Lanpher, Matthew Mervis, Madison Koval, Zachary Jager, Masaru Teramoto, Michael M. Green   +6 more
wiley   +1 more source

The function and mechanism of Human nasal mucosa-derived mesenchymal stem cells in allergic rhinitis in mice. [PDF]

Inflamm Res
Liu Y, Liu S, Meng L, Fang L, Yu J, Yue J, Li T, Tu Y, Jiang T, Yu P, Wan YZ, Lu Y, Shi L.   +12 more
europepmc   +1 more source

Effects of proton therapy on the tumor immune system and clinical implications: A review

Precision Radiation Oncology, EarlyView.
Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu, Mei Tao, Min Fu, Yingjia Hu, Zhen Tao, Guangyuan Hu   +5 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Validated HPLC method for simultaneous determination of azelastine hydrochloride fluticasone propionate and oxymetazoline in nasal mucosa and nasopharyngeal swabs from real human samples. [PDF]

Sci Rep
Mikawy NN, Magdy N, Mohamed MH, El-Kosasy AM.   +3 more
europepmc   +1 more source

Predictability of obstructive sleep apnea with a somesthetic screening score: Development and preliminary validation in a prospective study

Sleep Research, EarlyView.
This prospective study developed a two‐step clinical scoring system for obstructive sleep apnea (OSA) screening based on patients’ somesthetic perception of oropharyngeal airflow. The Intermediate Score (IS ≥ 7.5) achieved 73% sensitivity and 77% specificity (AUC = 0.7754; OR = 8.96).
Cédric Garcion, Alain Piron, Alain Lacroix, Bassam Chakar, Christophe Di Piazza   +4 more
wiley   +1 more source