Results 241 to 250 of about 602,823 (332)

Genetic Diagnosis and Clinical Features of Fetuses With Congenital Diaphragmatic Hernia

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Congenital diaphragmatic hernia (CDH) is a rare abnormality with highly heterogeneous genetic causes. This study investigated chromosomal and monogenic abnormalities in fetal CDH patients and evaluated the efficacy of chromosomal microarray analysis (CMA) and whole‐exome sequencing (WES) for genetic diagnosis.
Yan Lü   +18 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Effect of Hydrogen Peroxide on Guinea Pig Nasal Mucosa Vasculature

open access: gold, 2000
Tomohisa Hirai   +6 more
openalex   +1 more source

A Unified Whole Lung PBK Model for Inhalational Uptake of Gases and Aerosols in Men

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Assessing the risk or benefit of an inhaled substance is challenging due to the variety of forms it can take (gas, vapor, particle, or droplet) and the complex biological processes involved in its uptake and retention. Physiologically based kinetic (PBK) models offer an alternative to in vivo experiments.
Norman Nowak   +2 more
wiley   +1 more source

Coordinated nasal mucosa-mediated immunity accelerates recovery from COVID-19. [PDF]

open access: yesERJ Open Res
Cass SP   +10 more
europepmc   +1 more source

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