ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou +4 more
wiley +1 more source
Paradoxical psoriasiform dermatitis involving the nasal mucosa in the setting of infliximab for inflammatory bowel disease. [PDF]
Jacob-George S +4 more
europepmc +1 more source
Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu +7 more
wiley +1 more source
Transcriptomic Profiles of the Nasal Mucosa Following Birch Pollen Provocation Differ Between Birch Pollen-Allergic and Non-Allergic Individuals. [PDF]
Sudharson S +10 more
europepmc +1 more source
Differential expression pattern of antimicrobial peptides in nasal mucosa and secretion
Martin Laudien +3 more
openalex +2 more sources
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan +9 more
wiley +1 more source
Inflammation of the nasal mucosa is associated with susceptibility to experimental pneumococcal challenge in older adults. [PDF]
Urban BC +17 more
europepmc +1 more source
Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang +3 more
wiley +1 more source
The function and mechanism of Human nasal mucosa-derived mesenchymal stem cells in allergic rhinitis in mice. [PDF]
Liu Y +12 more
europepmc +1 more source

