Results 81 to 90 of about 602,823 (332)

SENSATION OF THE NASAL MUCOSA

open access: yesNippon Jibiinkoka Gakkai Kaiho, 1962
Aiming to resolve the problem on sensation of the nasal mucosa, the anterior part of the inferior turbinate was stimulated with rectangular pulse generated from an electrostimulator, and the subjective threshold of intensity (volt) and the objective observation with GSR were measured in normal, sinusitis, atrophic rhinitis, hypertrophic rhinitis etc.A ...
openaire   +3 more sources

A Single‐Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer's Disease via Intranasal Administration

open access: yesAdvanced Science, EarlyView.
Herein, guanidinium‐modified calix[5]arene (GC5AY) is developed featuring small size, positive charge, and desirable amphiphilicity, that can efficiently traverse the nasal mucosal barrier for brain drug delivery. Additionally, possessing inherent therapeutic functions, GC5AY can thus serve as a single‐molecule pleuripotent scaffold for multi‐target ...
Jian‐Mei Gao   +11 more
wiley   +1 more source

Effects of antihistamine on up-regulation of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit

open access: yesJournal of Pharmacological Sciences, 2015
In the present study, we examined the effects of antihistamine on the up-regulation of H1R mRNA in the nasal mucosa of patients with pollinosis induced by controlled exposure to pollen using an environmental exposure unit.
Yoshiaki Kitamura   +7 more
doaj   +1 more source

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent   +27 more
wiley   +1 more source

Ozone Induces Oxidative Stress and Inflammation in Nasal Mucosa of Rats

open access: yesAtmosphere
Background: The development of the global economy has led to changes in air pollution patterns. The haze phenomenon characterized by high concentrations of particulate matter 2.5 (PM2.5) has changed to complex pollution, and photochemical pollution ...
Yu Zhan   +4 more
doaj   +1 more source

Do Skin Prick Tests Predict Nasal Provocation Test Outcomes in Allergic Rhinitis Patients?

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background In diagnosing allergic rhinitis (AR), conventional skin prick tests (SPTs) often fail to reflect allergen‐induced nasal symptoms. Conversely, nasal provocation tests (NPTs) provide more definitive assessments but are less accessible.
Yunhyung Lee   +3 more
wiley   +1 more source

Expression and Roles of MMP-2, MMP-9, MMP-13, TIMP-1, and TIMP-2 in Allergic Nasal Mucosa

open access: yesAllergy Asthma and Immunology Research, 2012
Purpose Allergic rhinitis (AR) and asthma share many characteristics, but structural changes are observed far less often in AR. Matrix metalloproteinases (MMPs) constitute a family of Zn-dependent endopeptidases that can decompose the extracellular ...
S. Mori   +5 more
semanticscholar   +1 more source

Selective PAR2 Inhibition Attenuates HDM‐Induced Th1/Th2 Responses in Human Epithelial and Murine Models of Allergic Rhinitis and Asthma

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Allergic rhinitis (AR) and asthma are involved in complex interactions between Th1 and Th2 inflammatory pathways. House dust mite (HDM) activates protease‐activated receptor 2 (PAR2) to trigger inflammatory responses, but current treatments often provide inadequate control.
Miran Kang   +8 more
wiley   +1 more source

Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis Expressão de RANTES, eotaxina-2, ICAM-1, LFA-1 e CCR-3 em pacientes com rinossinusite crônica associada à polipose nasossinusal

open access: yesActa Cirúrgica Brasileira, 2012
PURPOSE: To compare gene expression of the chemokines RANTES and eotaxin-2, its receptor, CCR-3, adhesion molecule ICAM-1 and its receptor LFA-1 in eosinophilic polyps and in control normal nasal mucosa.
Fransérgio Emílio Cavallari   +8 more
doaj   +1 more source

Electrical Stimulation of Trigeminal Nerve at the Anterior Nasal Septum in Healthy Individuals and Patients With Olfactory Dysfunction

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The intranasal trigeminal system contributes to the sense of smell. Its integrity in olfactory dysfunction (OD) may be crucial for future treatments. This study assessed trigeminal sensitivity in healthy individuals and patients with OD of different etiologies using electrical stimulation of the nasal mucosa.
Konstantinos Garefis   +12 more
wiley   +1 more source

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