Results 61 to 70 of about 9,405 (123)
A Nasal Cytology Dataset for Object Detection and Deep Learning [PDF]
arXivNasal Cytology is a new and efficient clinical technique to diagnose rhinitis and allergies that is not much widespread due to the time-consuming nature of cell counting; that is why AI-aided counting could be a turning point for the diffusion of this technique.
arxiv
On computational fluid dynamics models for sinonasal drug transport: relevance of nozzle subtraction and nasal vestibular dilation [PDF]
arXiv, 2017 Generating anatomically realistic three-dimensional (3D) models of the human sinonasal cavity for numerical investigations of sprayed drug transport presents a host of methodological ambiguities. For example, subject-specific radiographic images used for 3D reconstructions typically exclude spray bottles.
arxiv
MTSS2‐Related Disorder: Refining the Phenotype in Four New Cases and Literature Review
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT MTSS2 encodes a protein highly expressed in the central nervous system, with a crucial role in neurodevelopment. The de novo recurrent variant c.2011C>T (p.Arg671Trp) was first identified in 2022 as cause of Intellectual Developmental Disorder with ocular anomalies and distinctive facial features (OMIM#620086).
Angela De Dominicis +12 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT HNRNPU‐related neurodevelopmental disorder (HNRNPU‐NDD) is caused by pathogenic and likely pathogenic variants in HNRNPU. With increasing accessibility to advanced genetic investigations, children presenting with developmental delay and intellectual disability will often undergo genomic testing; hence, the number of patients found to be ...
A. K. O. Hodgson +14 more
wiley +1 more source
Drug Testing and Analysis, Volume 14, Issue 11-12, Page 2007-2016, November-December 2022., 2022 In this work, excretion profile of prednisone and prednisolone was evaluated in subjects in therapy with glucocorticoids‐based rectal formulations. The absorption rate and the systemic bioavailability of an active principle after rectal administration are strongly influenced by the type of formulations and the physiological conditions of the absorption
Loredana Iannella +6 more
wiley +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Dysbiosis of the bacterial and fungal microbiome has been increasingly implicated in the pathogenesis of chronic rhinosinusitis (CRS). This study explores the relationship between microbiome and mycobiome biodiversity and type 2 (T2) versus non‐type 2 (NT2) inflammation.
Hong‐Ho Yang +13 more
wiley +1 more source
Machine learning of endoscopy images to identify, classify, and segment sinonasal masses
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background We developed and assessed the performance of a machine learning model (MLM) to identify, classify, and segment sinonasal masses based on endoscopic appearance. Methods A convolutional neural network‐based model was constructed from nasal endoscopy images from patients evaluated at an otolaryngology center between 2013 and 2024 ...
Lirit Levi +10 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Angewandte Chemie, EarlyView.Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog +8 more
wiley +2 more sources
Elexacaftor–Tezacaftor–Ivacaftor Improves Sinonasal Outcomes in Young Children With Cystic Fibrosis
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Severe chronic rhinosinusitis (CRS) is a near universal manifestation of cystic fibrosis. Elexacaftor/tezacaftor/ivacaftor (ETI) is an oral, small molecule, highly effective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) corrector–potentiator drug.
Amanda L. Stapleton +10 more
wiley +1 more source
EcoMat, Volume 5, Issue 2, February 2023., 2023 In this paper, a self‐powered virtual olfactory generation system is fabricated based on an ultrafast voltage‐elevation triboelectric nanogenerator. This system has two operation chambers, where the electrospray devices are in the front chamber and the electrostatic‐field accelerated evaporation process is occurred in the back.
Peng Yang +6 more
wiley +1 more source