Results 81 to 90 of about 9,405 (123)

Dosage‐dependent effects of FGFR2W290R mutation on craniofacial shape and cellular dynamics of the basicranial synchondroses

The Anatomical Record, EarlyView.
Abstract Craniosynostosis is a common yet complex birth defect, characterized by premature fusion of the cranial sutures that can be syndromic or nonsyndromic. With over 180 syndromic associations, reaching genetic diagnoses and understanding variations in underlying cellular mechanisms remains a challenge.
Heather A. Richbourg, Marta Vidal‐García, Katherine A. Brakora, Jay Devine, Risa Takenaka, Nathan M. Young, Siew‐Ging Gong, Amanda Neves, Benedikt Hallgrímsson, Ralph S. Marcucio   +9 more
wiley   +1 more source

Radiofrequency Ablation of Inferior Turbinates With Laser Posterior Nasal Nerve Neurolysis for the Treatment of Chronic Rhinitis

International Forum of Allergy &Rhinology, EarlyView.
Yi‐Li Hwang, Jyun‐Yi Liao, Ying‐Shuo Hsu, Ming‐Shao Tsai, Ting‐Yu Shih, Han‐Lo Teng, Bor‐Hwang Kang, Chien‐Yu Huang   +7 more
wiley   +1 more source

Comparing cranial biomechanics between Barbourofelis fricki and Smilodon fatalis: Is there a universal killing‐bite among saber‐toothed predators?

The Anatomical Record, EarlyView.
Abstract Saber‐tooths, extinct apex predators with long and blade‐like upper canines, have appeared iteratively at least five times in the evolutionary history of vertebrates. Although saber‐tooths exhibit a relatively diverse range of morphologies, it is widely accepted that all killed their prey using the same predatory behavior. In this study, we CT‐
Borja Figueirido, Shane Tucker, Stephan Lautenschlager   +2 more
wiley   +1 more source

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

The Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum, Michael J. Blumer, Mason N. Dean, Laura J. Ekstrom   +3 more
wiley   +1 more source

Disparity of turbinal bones in placental mammals

The Anatomical Record, EarlyView.
Abstract Turbinals are key bony elements of the mammalian nasal cavity, involved in heat and moisture conservation as well as olfaction. While turbinals are well known in some groups, their diversity is poorly understood at the scale of placental mammals, which span 21 orders.
Quentin Martinez, Mark Wright, Benjamin Dubourguier, Kai Ito, Thomas van de Kamp, Elias Hamann, Marcus Zuber, Gabriel Ferreira, Rémi Blanc, Pierre‐Henri Fabre, Lionel Hautier, Eli Amson   +11 more
wiley   +1 more source

De novo putative loss‐of‐function variants in TAF4 are associated with a neuro‐developmental disorder

Human Mutation, Volume 43, Issue 12, Page 1844-1851, December 2022., 2022
Abstract TATA‐binding protein associated factor 4 (TAF4) is a subunit of the Transcription Factor IID (TFIID) complex, a central player in transcription initiation. Other members of this multimeric complex have been implicated previously as monogenic disease genes in human developmental disorders.
Beau D. E. Janssen, Marie‐Jose H. van den Boogaard, Klaske Lichtenbelt, Eleanor G. Seaby, Karen Stals, Sian Ellard, Ruth Newbury‐Ecob, Abhijit Dixit, Laura Roht, Sander Pajusalu, Katrin Õunap, Helen V. Firth, Michael Buckley, Meredith Wilson, Tony Roscioli, Timothy Tidwell, Rong Mao, Sarah Ennis, Sjoerd J. Holwerda, Koen van Gassen, Richard H. van Jaarsveld   +20 more
wiley   +1 more source

Helmeted hornbill cranial kinesis: Balancing mobility and stability in a high‐impact joint

The Anatomical Record, EarlyView.
Abstract Prokinesis—in which a craniofacial joint allows the rostrum to move relative to the braincase—is thought to confer diverse advantages in birds, mostly for feeding. A craniofacial joint would, however, be a weak link if cranial stability is important. Paradoxically, we have identified a craniofacial joint in helmeted hornbills (Rhinoplax vigil),
Mike Schindler, Benjamin Flaum, Armita Razieh Manafzadeh, Viktoriia Kamska, Kanmani Chandra Rajan, Maria Jose Robles Malagamba, Ruien Hu, Daniel Baum, Mason N. Dean   +8 more
wiley   +1 more source

Segmentation of cortical bone, trabecular bone, and medullary pores from micro‐CT images using 2D and 3D deep learning models

The Anatomical Record, EarlyView.
Abstract Computed tomography (CT) enables rapid imaging of large‐scale studies of bone, but those datasets typically require manual segmentation, which is time‐consuming and prone to error. Convolutional neural networks (CNNs) offer an automated solution, achieving superior performance on image data.
Andrew H. Lee, Julian M. Moore, Brandon Vera Covarrubias, Leigha M. Lynch   +3 more
wiley   +1 more source

Early life functional transitions impact craniofacial morphology in osteogenesis imperfecta

The Anatomical Record, EarlyView.
Abstract Early life behaviors have a profound role in shaping adult craniofacial morphology. During early life, all mammals undergo the dynamic transition from suckling to mastication, a period coinciding with rapid cranial biomineralization. Osteogenesis imperfecta (OI), a genetic disorder that impacts the production of type I collagen, disrupts ...
Courtney A. Miller, Tanusha Emanuel, Rachel A. Menegaz   +2 more
wiley   +1 more source

Linking individual variation in facial musculature to facial behavior in rhesus macaques

The Anatomical Record, EarlyView.
Abstract Facial expression is a key component of primate communication, and primates (including humans) have a complex system of facial musculature underpinning this behavior. Human facial musculature is highly variable across individuals, but to date, whether other primate species exhibit a similar level of inter‐individual variation is unknown ...
Clare M. Kimock, Charles Ritchie, Jamie Whitehouse, Claire Witham, Claire M. Tierney, Nathan Jeffery, Bridget M. Waller, Anne M. Burrows   +7 more
wiley   +1 more source