Clinical effectiveness of dupilumab in CRSwNP: unaffected by baseline nasal polyp size in real-world settings. [PDF]
Eur Arch OtorhinolaryngolHabenbacher M +8 more
europepmc +1 more source
JEADV Clinical Practice, Volume 5, Issue 1, Page 194-197, March 2026.ABSTRACT Background Chronic spontaneous urticaria (CSU) is a mast cell‐driven condition defined by recurrent wheals and/or angioedema lasting over 6 weeks without an identifiable trigger. Though CSU is known to co‐occur with atopic diseases and share Th2‐dominant immunologic pathways, prior studies have not adequately addressed these relationships in ...
Julian A. Cortes +4 more
wiley +1 more source
Efficacy of Additional (Selective) Vidian Neurectomy in Treating Chronic Rhinosinusitis with Nasal Polyp: A Systematic Review and Meta-Analysis. [PDF]
ORL J Otorhinolaryngol Relat SpecKim DH, Jang DW, Hwang SH.
europepmc +1 more source
Long‐Term Cost Utility Analysis of Endoscopic Sinus Surgery: Analysis of 5‐Year Outcomes
The Laryngoscope, Volume 136, Issue 3, Page 1141-1149, March 2026.This study utilizes a cohort‐style Markov decision tree economic model to evaluate the long‐term (5‐year) cost‐effectiveness of endoscopic sinus surgery versus medical management for patients with chronic rhinosinusitis. The results show that the endoscopic sinus surgery strategy cost more ($63,296.27) but yielded increased quality‐adjusted life years (
Dara R. Adams +5 more
wiley +1 more source
Actinomycosis masquerading as a nasal polyp - a rare entity and diagnostic challenge. [PDF]
GMS Hyg Infect ControlSakthimohan R +3 more
europepmc +1 more source
Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients
The Laryngoscope, Volume 136, Issue 3, Page 1150-1157, March 2026.ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma +7 more
wiley +1 more source
Correlation Between Smell Recovery and Nasal Polyp Score in Patients Treated with Dupilumab: A Real-Life Retrospective, Observational, Monocentric Study. [PDF]
J Pers MedStilo G +11 more
europepmc +1 more source
Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD
The Laryngoscope, Volume 136, Issue 3, Page 1126-1133, March 2026.The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne +3 more
wiley +1 more source
Biologic Therapies across Nasal Polyp Subtypes. [PDF]
J Pers MedBolk KG, Wise SK.
europepmc +1 more source
Otolaryngology–Head and Neck Surgery, Volume 174, Issue 3, Page 671-677, March 2026.Abstract Objective Previous studies have suggested a benefit to early functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis (CRS). With the approval of T2 biologics for CRS with nasal polyps (CRSwNP), it is important to re‐evaluate FESS timing in relation to T2 biologic utilization.
Radhika Duggal +4 more
wiley +1 more source