Results 161 to 170 of about 375,973 (338)

بررسی عفونت مايکوپلاسما و کلاميديا به روش PCR و سرولوژی در نسج پوليپ بيماران و مخاطبين افراد غير مبتلا [PDF]

open access: yes, 2009
زمينه و هدف: در مورد پاتوژنز رينوسينوزيت‌های مزمن و پوليپ‌ بينی، وجود زمينه التهابی تا حدودی مسجل است، ولی عوامل قطعی آن همچنان ناشناخته‌اند. در اين تحقيق، از بين عوامل عفونی دو باکتری مايکوپلاسما و کلاميديا که نقش عمده‌ای در انواع بيماری‌های دستگاه ...
شمشيری, رضا   +6 more
core  

The Utility of Intranasal Corticosteroids in Association With Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis: A Real‐Life Multicenter Study by a Tuscany Group

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando   +17 more
wiley   +1 more source

Broad IgG repertoire in patients with chronic rhinosinusitis with nasal polyps regulates proinflammatory IgE responses [PDF]

open access: bronze, 2019
Mohamed H. Shamji   +9 more
openalex   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

open access: yesAllergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng   +20 more
wiley   +1 more source

Tuft cells in the pathogenesis of chronic rhinosinusitis with nasal polyps and asthma

open access: green, 2020
Elizabeth Sell   +3 more
openalex   +2 more sources

Dupilumab improves nasal polyp burden and asthma control in patients with CRSwNP and AERD.

open access: yesJournal of Allergy and Clinical Immunology: In Practice, 2019
T. Laidlaw   +7 more
semanticscholar   +1 more source

Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms

open access: yesAllergy, EarlyView.
The Allergic Rhinitis and its Impact on Asthma (ARIA) group is working on the 2024–2025 update of its guidelines for the management of allergic rhinitis (ARIA 2024–2025). The ARIA 2024–2025‐EAACI guidelines will follow GRADE methodology and will incorporate evidence from different sources, including systematic reviews and meta‐analyses, mHealth data ...
Jean Bousquet   +230 more
wiley   +1 more source

Rhinosporidiosis presenting as an urethral polyp [PDF]

open access: yes, 2008
Rhinosporidiosis is an inflammatory disease caused by Rhinosporidium seeberi, a protoctistan mesomycetozoa, member of a group of novel aquatic parasites, characterized by hyperplastic polypoid lesions of the nasal cavity and rarely other mucous membranes.
Ahmad, Zubairali   +2 more
core   +1 more source

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

open access: yesAllergy, EarlyView.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang   +13 more
wiley   +1 more source

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