Results 1 to 10 of about 404,841 (308)

Remodeling in Chronic Sinusitis and Nasal Polyps

Allergology International, 2005
Remodeling in chronic sinusitis and nasal polyps is discussed. In chronic sinusitis, epithelial shedding, which is characteristic of asthma, is not observed in the maxillary sinus.
Kazuhiko Takeuchi, Yuichi Majima
doaj   +2 more sources

Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps [PDF]

Respiratory Research, 2009
Background Decreased infiltration of Foxp3+ T regulatory cell (Treg) is considered to be critical for the Th1/Th2 dysregulation of nasal polyps, while the cellular mechanism underlying Foxp3+ Treg insufficiency is currently not well defined.
Shi Jianbo, Cai Kemin, Liu Zheng, Yu Chuanzhao, Hua Xiaoyang, Zhou Han, Xia Jiahong, Xu Geng, Li Huabin   +8 more
doaj   +2 more sources

PREVALENCE OF NASAL POLYPS IN CHRONIC RHINOSINUSITIS PATIENTS UNDERGOING FUNCTIONAL ENDOSCOPIC SINUS SURGERY

Interdisciplinary Approaches to Medicine, 2021
Chronic Rhinosinusitis (CRS) is a common disease that affects a large percentage of the population, Nasal obstruction, nasal discharge, headache and the decline in quality of life are all symptoms that have social and economic consequences.
Abdul Azeem Rasouli, Dyamely Zhaisakova
doaj   +3 more sources

The causal relationship between multiple autoimmune diseases and nasal polyps

Frontiers in Immunology, 2023
BackgroundAlthough previous sporadic studies have reported the associations between a few autoimmune diseases and nasal polyps, these studies have limitations such as conflicting results, small sample sizes, and low levels of evidence.MethodsSeveral ...
Siyuan Chen, Lu Tan, Danxue Qin, Hao Lv, Kunyu Liu, Yingying Xu, Xiaomin Wu, Jingyu Huang, Yu Xu, Yu Xu, Yu Xu, Yu Xu   +11 more
doaj   +1 more source

EPOS/EUFOREA update on indication and evaluation of Biologics in Chronic Rhinosinusitis with Nasal Polyps 2023.

Rhinology, 2023
Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a significant impact on the quality of life (QoL). It is typically characterized by a type 2 inflammatory reaction and by comorbidities such as asthma, allergies and ...
W. Fokkens, A. Viskens, Vibeke Backer, D. Conti, E. Corso, P. Gevaert, G. Scadding, Martin Wagemann, Manuel Bernal - Sprekelsen, A. Chaker, E. Heffler, Joseph K. Han, E. V. Staeyen, C. Hopkins, J. Mullol, A. Peters, S. Reitsma, B. Senior, P. Hellings   +18 more
semanticscholar   +1 more source

Dupilumab in the treatment of severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP): A multicentric observational Phase IV real‐life study (DUPIREAL)

Allergy. European Journal of Allergy and Clinical Immunology, 2023
Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with significant morbidity and reduced health‐related quality of life. Findings from clinical trials have demonstrated the effectiveness of dupilumab in CRSwNP, although real‐world evidence ...
E. de Corso, E. Pasquini, M. Trimarchi, I. La Mantia, F. Pagella, G. Ottaviano, M. Garzaro, C. Pipolo, S. Torretta, V. Seccia, E. Cantone, A. Ciofalo, D. Lucidi, G. Fadda, P. Pafundi, S. Settimi, C. Montuori, F. Anastasi, G. Pagliuca, A. Ghidini, C. Cavaliere, M. Maffei, F. Bussu, S. Gallo, Frank Rikky Mauritz Canevari, G. Paludetti, J. Galli   +26 more
semanticscholar   +1 more source

The roles of eosinophils and interleukin‐5 in the pathophysiology of chronic rhinosinusitis with nasal polyps

International Forum of Allergy and Rhinology, 2022
Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with eosinophilic tissue infiltration linked to type 2 inflammation and characterized by elevated levels of interleukin (IL)‐5 and other type 2 inflammatory mediators.
P. Gevaert, Joseph K. Han, Steven G. Smith, A. Sousa, P. Howarth, S. Yancey, R. Chan, C. Bachert   +7 more
semanticscholar   +1 more source

Burden of Disease in Chronic Rhinosinusitis with Nasal Polyps

Journal of Asthma and Allergy, 2021
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a predominantly type 2 inflammation-mediated disease of the nasal mucosa and paranasal sinuses with an under-recognized clinical, humanistic, and economic burden. Patients with CRSwNP experience a high
C. Bachert, N. Bhattacharyya, M. Desrosiers, Asif H Khan   +3 more
semanticscholar   +1 more source

Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): In‐depth sinus surgery analysis

Allergy. European Journal of Allergy and Clinical Immunology, 2022
Patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) often require repeat sinus surgery. Mepolizumab reduced the need for sinus surgery in the SYNAPSE trial; this analysis sought to provide a more in‐depth assessment of surgery ...
W. Fokkens, J. Mullol, D. Kennedy, C. Philpott, V. Seccia, R. Kern, A. Coste, A. Sousa, P. Howarth, Victoria S Benson, B. Mayer, S. Yancey, R. Chan, S. Gane   +13 more
semanticscholar   +1 more source

A Child who has Nasal Polyposis Combined with Bronchiectasis [PDF]

Journal of Rhinology, 2020
Nasal polyps are inflammatory lesions of sinonasal tissue that are associated with chronic rhinosinusitis, allergic reaction, and other diseases. Although it is the most common cause of nasal polyps, chronic inflammation of the nasal cavity is not common
Sangjun Kim, Daeyeon Kim, Woo Yong Bae, Jin-A Jung   +3 more
doaj   +1 more source