Results 51 to 60 of about 62,516 (342)

Transforming Patient Experience: Real-World Impact of Mepolizumab on Symptom Burden in Chronic Rhinosinusitis with Nasal Polyps—A Multicenter Perspective [PDF]

open access: greenJ Clin Med
García-Piñero A   +16 more
europepmc   +3 more sources

Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]

open access: yes, 2013
Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A   +2 more
core   +2 more sources

Oral and Nasal Steroids for Nasal Polyps [PDF]

open access: yesCurrent Allergy and Asthma Reports, 2011
Trial: Vaidyanathan S, Barnes M, Williamson P, et al.: Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial. Ann Intern Med 2011; 154:293–302. Rating: •Of importance. Introduction: Chronic rhinosinusitis (CRS) with nasal polyps is a common form of the disorder with distinct ...
openaire   +2 more sources

Cadherin‐26 Facilitates Transepithelial Migration of Eosinophils in Eosinophilic Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo   +7 more
wiley   +1 more source

Cytokine and Lipid Mediator Regulation of Group 2 Innate Lymphoid Cells (ILC2s) in Human Allergic Airway Disease. [PDF]

open access: yes, 2017
The recent discovery of group 2 innate lymphoid cells (ILC2s) has caused a paradigm shift in the understanding of allergic airway disease pathogenesis.
Cavagnero, Kellen, Doherty, Taylor A
core   +2 more sources

Machine Learning‐Enhanced Clinical Decision Support for Diagnosing Sinusitis With Nasal Endoscopy

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinusitis is a prevalent disease for which nasal endoscopy (NE) is an optimal diagnostic modality. However, NE accuracy is limited by inter‐operator variability in landmark identification and localization of mucus that is necessary for sinusitis diagnosis. We sought to develop a novel multi‐class machine learning (ML) framework that
Dipesh Gyawali   +12 more
wiley   +1 more source

Immune Imbalance in Nasal Polyps of Caucasian Chronic Rhinosinusitis Patients Is Associated with a Downregulation of E-Selectin

open access: yesJournal of Immunology Research, 2014
Chronic rhinosinusitis with nasal polyps (CRSwNP) in Caucasians is a chronic Th2 inflammatory disease of the nasal and paranasal mucosa and the recruitment of leukocytes to the site of inflammation is poorly understood.
Michael Könnecke   +6 more
doaj   +1 more source

Expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in recurrent chronic rhinosinusitis with nasal polyposis

open access: yesKaohsiung Journal of Medical Sciences, 2013
Matrix metalloproteinase (MMP) is involved in the upper airway remodeling process. We hypothesized that MMP had an additive effect on the formation of recurrent nasal polyp.
Ling-Feng Wang   +4 more
doaj   +1 more source

MicroRNAs: Potential Biomarkers of Disease Severity in Chronic Rhinosinusitis with Nasal Polyps

open access: yesMedicina, 2023
Background and Objectives: Chronic rhinosinusitis with nasal polyps (CRwNP) has multiple clinical presentations, and predictors of successful treatment are correlated to different parameters.
Anda Gata   +6 more
doaj   +1 more source

Mediators and Cytokines in Persistent Allergic Rhinitis and Nonallergic Rhinitis with Eosinophilia Syndrome [PDF]

open access: yes, 2012
Background: Patients with nonallergic rhinitis with eosinophilia syndrome (NARES) show typical symptoms of persistent allergic rhinitis (PAR). The aim of the present study was to compare nasal cytokine patterns between NARES and PAR.
Becker, Sven   +8 more
core   +1 more source

Home - About - Disclaimer - Privacy