Results 51 to 60 of about 42,582 (233)

Nasal Dermoplasty for Recurrent Polyps in a Patient with Churg-Strauss Syndrome

Case Reports in Otolaryngology, 2015
Nasal dermoplasty for recurrent polyps (NDRP) is a new technique for the surgical treatment of this condition. Churg-Strauss syndrome is characterized by the presence of nasal polyps with a great tendency for relapse after surgical or pharmaceutical ...
George Anastasopoulos, Theophanis Machas, Sofia Kegioglou, Demetra Rapti   +3 more
doaj   +1 more source

Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps

Respiratory Research, 2009
Background Decreased infiltration of Foxp3+ T regulatory cell (Treg) is considered to be critical for the Th1/Th2 dysregulation of nasal polyps, while the cellular mechanism underlying Foxp3+ Treg insufficiency is currently not well defined.
Shi Jianbo, Cai Kemin, Liu Zheng, Yu Chuanzhao, Hua Xiaoyang, Zhou Han, Xia Jiahong, Xu Geng, Li Huabin   +8 more
doaj   +1 more source

Linking Complement C3 and B Cells in Nasal Polyposis

Journal of Immunology Research, 2020
Nasal polyposis often is characterized by a persistent inflammation of the sinonasal mucosa, disease recurrence after medical or surgical intervention, and asthma comorbidity.
Ulrike Werner, Axel Künstner, Maren Drenckhan, Ralph Pries, Karl-Ludwig Bruchhage, Hauke S. Busch, Claus Bachert, Barbara Wollenberg   +7 more
doaj   +1 more source

Nasal polyps. [PDF]

BMJ, 1973
  +9 more sources

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Accepted Article.
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Heredity of nasal polyps

Rhinology journal, 2015
Background: Nasal polyps is a common disease but little is known about its` pathogenesis. Our hypothesis was that there are genetic factors involved in the development of this disease. The aim of this study was to examine close relatives of patients with nasal polyps and comparing them with a general population with regard to prevalence of polyps ...
Anton, Bohman, Martin, Oscarsson, Kenneth, Holmberg, Leif, Johansson, Eva, Millqvist, Salmir, Nasic, Åsa, Torinsson-Naluai, Mats, Bende   +7 more
openaire   +3 more sources

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

Nasal polyps show decreased mucociliary transport despite vigorous ciliary beating

Brazilian Journal of Otorhinolaryngology
Objective: Mucociliary transport function in the airway mucosa is essential for maintaining a clean mucosal surface. This function is impaired in upper and lower airway diseases.
Thi Nga Nguyen, Yuma Koga, Tetsuro Wakasugi, Takuro Kitamura, Hideaki Suzuki   +4 more
doaj   +1 more source

Estudo de 92 casos de polipo nasal de tipo alergico. Uma metedologia para a sua caracterização etiológica.

Acta Médica Portuguesa, 1995
The etiopathogenesis of nasal allergic polyps is poorly understood; an immunological mediated mechanism is commonly admitted. A clinic-pathological study of 92 cases of nasal polyps is reported.
J C Pimentel
doaj   +1 more source

Surmounting Recalcitrant Airway Inflammatory Disorders With a Multi‐Targeting Therapeutic Strategy by Tannic Acid‐Modified CuInP2S6 Nanosheets

Exploration, EarlyView.
Our findings underscore a multi‐targeting strategy for severe airway inflammation that multi‐targeting nanoformulation C‐TA1 markedly attenuated airway inflammation by (1) cfDNA elimination to alleviate neutrophilic/eosinophilic inflammation mediated by the TLR9 pathway, (2) prevention of RONS‐induced tissue injury and inflammatory response, (3 ...
Ming Liu, Changyi Xu, Renqiang Ma, Xinran Xie, Ying Xie, Mengya Du, Zhaofeng Xu, Shuaiyin Zhang, Jian Li, Weiping Wen, Zhaoxu Tu   +10 more
wiley   +1 more source