Results 81 to 90 of about 42,582 (233)

From Expectations to Experience: A Comparison of Program Director Priorities to Resident Case Logs

The Laryngoscope, EarlyView.
The present study identified 47 essential otolaryngology procedures via program director surveys and evaluated the extent of resident participation in these cases through ACGME case logs. Results revealed significant variability in surgical experience, with nearly half of these essential procedures being logged fewer than 10 times during residency ...
Taylor S. Erickson, Yoon Soo Park, Sean Hogan, Sophie Yu, Steven D. Pletcher, Sonya Malekzadeh, Stacey T. Gray, Jenny X. Chen   +7 more
wiley   +1 more source

Radiofrequency Ablation Versus Laser Neurolysis of the Posterior Nasal Nerve in Patients With Chronic Rhinitis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the clinical outcomes of radiofrequency ablation of the intraturbinate segment of the posterior nasal nerve (RAPN) alone versus combined RAPN with CO₂ laser posterior nasal nerve neurolysis (RPN3) in patients with chronic rhinitis refractory to medical therapy. Study Design Retrospective cohort study.
Chia‐Chen Lin, Yi‐Li Hwang, Jyun‐Yi Liao, Han‐Lo Teng, Ting‐Yu Shih, Chien‐Yu Huang   +5 more
wiley   +1 more source

The Association Between Allergic Rhinitis, Eosinophilic Inflammation, and Postoperative Recurrence in Nasal Polyps

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Although allergic rhinitis (AR) commonly co‐occurs with chronic rhinosinusitis with nasal polyps (CRSwNP), its impact on tissue endotypes and prognosis remains unclear. This study examines the impact of AR on CRSwNP, focusing on its links to tissue eosinophilic inflammation and postoperative recurrence risk.
Wei Zhong, Shaobing Xie, Haijun He, Hua Zhang, Weihong Jiang, Can Liao, Zhihai Xie   +6 more
wiley   +1 more source

Comparison of BCL-2 protein expression in nasal polyp and chronic rhinosinusitis [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Chronic rhinosinusitis is a common inflammatory disorder affecting the sinonasal mucosa, which can develop with or without nasal polyps.
Hassan Alimoradi Sharifabadi, Mohammadreza Jalali Nadoushan, Motahareh Sedaghat Telgard   +2 more
doaj  

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

Respirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota, Keiko Kan‐o, Yumiko Ishii, Tomoaki Koga, Takeshi Sawada, Kei‐ichiro Yasunaga, Shingo Usuki, Tatsuya Katsuno, Shigesato Inoue, Tomohiro Ogawa, Akihiro Jo, Satoru Fukuyama, Mitsuyoshi Nakao, Hiroaki Ogata, Mizuho A. Kido, Sachiko Tsukita, Koichiro Matsumoto, Isamu Okamoto   +17 more
wiley   +1 more source

Deep Learning for Endoscopic Classification of Adenoid Hypertrophy

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Endoscopy is a convenient and widely used method to evaluate adenoid size, but the subjectivity of its image diagnosis can result in over‐ or underestimation. To create a new assessment strategy for adenoid hypertrophy, we developed a reliable method for automated classification using a deep learning algorithm with nasal endoscopic ...
Xuan‐Sheng Wang, De‐Sheng Jia, Zhi‐Xin Mo, Hong‐Ying Zheng, Zheng‐Jun Zhong, Guo Xu, Jing Chen, Zeng‐Kai Chen, Hong‐Guang Pan, Ze‐Bin Wu   +9 more
wiley   +1 more source

Variations in the Severity of Rhinitis Symptoms: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Key rhinitis symptoms include nasal obstruction, rhinorrhea, sneezing, and nasal itching. Different subtypes of rhinitis can have varying presentations, making it difficult to diagnose and categorize. The objective of this review is to characterize the baseline presentation of rhinitis and highlight differences in the presentation of
Asher T. Ripp, Pranav A. Patel, Shaun A. Nguyen, Isabella V. Schafer, Alexander N. Duffy, Zachary M. Soler, Rodney J. Schlosser   +6 more
wiley   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source