Results 81 to 90 of about 48,221 (285)

Impact of Early Versus Delayed Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyps

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Previous studies have suggested a benefit to early functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis (CRS). With the approval of T2 biologics for CRS with nasal polyps (CRSwNP), it is important to re‐evaluate FESS timing in relation to T2 biologic utilization.
Radhika Duggal   +4 more
wiley   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

open access: yesRheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

Clinicopathological Characteristics of Nasal Polyps with Chronic Sinusitis

open access: yesJournal of Bahria University Medical and Dental College, 2016
Objective: To evaluate the clinicopathological characteristics of nasal polyps associated with chronic sinusitis in polypectomy specimens. Materials and Methods: A total of 78 cases clinically presenting with signs and symptoms of chronic sinusitis with
Muhammad Tahir Khadim   +6 more
doaj  

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

open access: yesRespirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota   +17 more
wiley   +1 more source

Deep Learning for Endoscopic Classification of Adenoid Hypertrophy

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Endoscopy is a convenient and widely used method to evaluate adenoid size, but the subjectivity of its image diagnosis can result in over‐ or underestimation. To create a new assessment strategy for adenoid hypertrophy, we developed a reliable method for automated classification using a deep learning algorithm with nasal endoscopic ...
Xuan‐Sheng Wang   +9 more
wiley   +1 more source

The IL-4 mediated regulation of periostin in epithelial cells in chronic rhinosinusitis with nasal polyps

open access: hybrid, 2022
Karla Hegener   +4 more
openalex   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology   +4 more
wiley   +1 more source

Activation Of TLR4 Induces VEGF Expression Via Akt Pathway In Nasal Polyps [PDF]

open access: bronze, 2014
Jung‐Sun Cho   +5 more
openalex   +1 more source

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