Results 201 to 210 of about 2,419,788 (292)

Acute effects of THC and a CBD+THC combination on cardiovascular haemodynamics and respiratory muscle activity during loaded breathing in healthy adults: A randomized placebo‐controlled crossover study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the acute effects of cannabidiol plus tetrahydrocannabinol (CBD+THC) and tetrahydrocannabinol (THC) oils on cardiovascular haemodynamics, respiratory muscle activity and peripheral tissue perfusion in healthy adults. Methods In this randomized, double‐blind, crossover trial, participants received orally administered ...
Edna Karla Ferreira Laurentino, Marina Lyra L. C. Fagundes, Bruno Lobão Soares, Rodrigo Torres‐Castro, Matias Otto‐Yañez, Emerson Arcoverde Nunes, Matheus Freitas Fernandes Pedrosa, Jéssica Danielle Medeiros da Fonsêca, Vanessa R. Resqueti, Guilherme Augusto de Freitas Fregonezi   +9 more
wiley   +1 more source

Antimicrobial Resistance, Serotypes, Virulence Gene Profiles, and Molecular Characterization of <i>Streptococcus suis</i> Isolated from Healthy Pigs in Thailand. [PDF]

Antibiotics (Basel)
Saengsawang P, Tadee P, Patchanee P, Mitsuwan W, Boonmar S, Kabeya H, Kittiwan N, Warin R, Boripun R.   +8 more
europepmc   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Correlation of Patient-Reported Symptoms With Rhinogram Features Beyond Simple Airway Resistance. [PDF]

Ann Otol Rhinol Laryngol
Darbari Kaul R, Alvarado R, Choy C, Sun H, Liu S, Hua E, Grouse L, Haghighi M, Liang K, Zou E, Desai A, Campion NJ, Thiel C, Azemi G, Sacks R, Campbell RG, Kalish L, Di Ieva A, Harvey RJ.   +18 more
europepmc   +1 more source

Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences

British Journal of Clinical Pharmacology, EarlyView.
Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry, Muhammad Umair Khan, Barbara Conway, Syed Shahzad Hasan   +3 more
wiley   +1 more source

<i>Mannheimia haemolytica</i> strain-level diversity in cattle populations. [PDF]

Microbiol Spectr
Tamm SC, Doster E, Wolfe CA, Pinnell LJ, Crosby WB, Newcomer BW, Funk JL, Richeson JT, Gow SP, Valeris-Chacin R, Woolums AR, Morley PS.   +11 more
europepmc   +1 more source

Default Effect in ESG Investment: When a Recommendation Goes a Long Way

Business Strategy and the Environment, EarlyView.
ABSTRACT Individual investors display a positive attitude toward ESG investments but typically fail to act upon it. We report results from a preregistered online experiment testing a default option on 1050 US investors examining the mechanisms driving the effectiveness of default options in promoting ESG investments.
Sai Sravanthi Ramadugula, R. Prasantha Kumar, Luc Meunier   +2 more
wiley   +1 more source

The SPRR2A-CSTA axis drives IL-17A-induced squamous metaplasia and steroid resistance in allergic rhinitis. [PDF]

J Allergy Clin Immunol
Xie S, Yuan X, Liu L, Wu M, Gu W, Zhang H, Xie Z, Jiang W, Gao P.   +8 more
europepmc   +1 more source

Conceptualising Supply Chain Resilience Within Social Enterprises

Business Strategy and the Environment, EarlyView.
ABSTRACT This research seeks to conceptualise supply chain resilience (SCRes) in a social enterprise (SE) context, focusing on SEs with a social mission to tackle food insecurity and food poverty. Despite the increasingly mature field of SCRes and awareness of the critical role SEs play in tackling social challenges such as food poverty, no studies ...
Alexander James Jones, Helen Walker, Yingli Wang, Ken Peattie   +3 more
wiley   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source