Results 191 to 200 of about 7,607 (246)
Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.This review evaluates the clinical potential and limitations of intranasal (IN) drug administration in veterinary anaesthesia and emergency care. IN delivery can provide clinically relevant sedation, analgesia and drug reversal, but its success is not universally reliable and is strongly influenced by species‐specific anatomy, formulation ...
Majid Jafarbeglou
wiley +1 more source
Pre‐Sport Cardiac Evaluation in Children: Detection of Risks Other Than Sudden Cardiac Death
Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.In children who want to play sports, is a cardiac evaluation necessary only for sudden cardiac death? ABSTRACT Objective Sudden deaths may occur in children and adolescents due to unexpected cardiac problems during sports. This study aimed to screen for abnormalities that may lead to future morbidity in addition to the risk of sudden death and to ...
Mehmet Öncül, Abdulgani Gülyüz
wiley +1 more source
Investigating the Effect of Tumour Necrosis Factor Antagonist on Olfaction
Clinical Otolaryngology, Volume 51, Issue 4, Page 504-511, July 2026.ABSTRACT Objectives Tumour Necrosis factor antagonists is a potent anti‐inflammatory medication and has shown to improve olfactory function in murine models. The primary aim was to determine the effect of TNF antagonists on olfactory performance in humans.
Andreas Espehana +7 more
wiley +1 more source
Clinical Otolaryngology, Volume 51, Issue 4, Page 538-547, July 2026.ABSTRACT Objective and Design The growing demand for transparency about the efficacy of healthcare has accelerated the use of Patient‐Reported Outcome Measures (PROMs), but their integration into daily practice is challenging. This observational study describes how the Septoplasty Healthcare Monitor (SHM) addresses these challenges and highlights the ...
Victor S. van Dam +5 more
wiley +1 more source
Platelet‐Rich Fibrin Can Improve Septoplasty Results: A Prospective Randomised Controlled Trial
Clinical Otolaryngology, Volume 51, Issue 4, Page 548-554, July 2026.ABSTRACT Aim This study aims to assess the impact of platelet‐rich fibrin (PRF) on nasal mucociliary clearance (NMC) time and post‐operative pain following septoplasty. Patients and Methods This trial was conducted involving patients who underwent septoplasty. Participants were randomly assigned to either a control group or a PRF group.
Emre Solguntekin +3 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 7, July 2026.ABSTRACT This was a Phase 1, open label, randomized, crossover study to evaluate the safety and pharmacokinetics of multiple doses of intranasal naloxone (NCT05377255). Twenty‐four healthy participants were enrolled at a single site in the US to one of two sequences.
David Cassie +4 more
wiley +1 more source
Fundamental &Clinical Pharmacology, Volume 40, Issue 4, July 2026.ABSTRACT Background Cocaine use disorder (CUD) remains a major public health concern, characterized by high relapse rates and the absence of approved pharmacological treatments. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RA), widely prescribed for metabolic disorders, modulate mesolimbic reward pathways and have been proposed as potential ...
Céline Eiden +7 more
wiley +1 more source
Pubertal development and hypothalamic–pituitary–gonadal axis are altered in male mice lacking Mecp2
Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.Abstract Mutations in the MECP2 gene, encoding the epigenetic reader Methyl‐CpG binding protein 2, are the main cause of Rett syndrome, a rare neurodevelopmental disorder. Besides severe symptoms such as profound intellectual disability, loss of speech and motor skills, and epilepsy, loss of function of MECP2 has been associated with pubertal ...
Ana Martín‐Sánchez +6 more
wiley +1 more source
Orthopaedic Surgery, Volume 18, Issue 7, Page 1328-1341, July 2026.This largest Asian case series confirms that posterior spinal fusion for SMA scoliosis is safe and effective despite severe deformity and markedly impaired pulmonary function. Meticulous multidisciplinary care, including advanced airway planning, hemodynamic support, blood management, and proactive electrolyte correction, is critical to optimizing ...
Ai Hu +7 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 12, 30 June 2026.Retinoic acid (RA) regulates the positional identity of cranial neural crest cells (CNCCs) through the transcription factors Alx1 and Alx4. Upon receiving RA from the local environment, liganded RAR/RXR heterodimers activate the expression of Alx1 and Alx4, which promote the frontonasal identity of CNCCs and inhibit the first pharyngeal arch identity ...
Shuxuan Wu +7 more
wiley +1 more source