Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman +9 more
wiley +1 more source
Improving the efficacy of functional endoscopic sinus surgery in chronic rhinosinusitis with nasal polyps through the combination of budesonide infiltration therapy. [PDF]
Cun JJ +7 more
europepmc +1 more source
ABSTRACT Background The indication for nasal irrigation with corticosteroids after sinus surgery in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is well established, as surgery facilitates distribution throughout the sinonasal cavity.
Juliana Sant'Ana +5 more
wiley +1 more source
Novel approach for assessing nasal valve obstruction: a study of nasal valve patency using peak nasal inspiratory flow and flowmetry. [PDF]
Knížek Z +4 more
europepmc +1 more source
Rationale of New Grading System: Central Compartment Atopic Disease
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna +11 more
wiley +1 more source
Nasal Sublesional Bevacizumab Injections as Adjuvant Treatment for Diffuse Sinonasal Exophytic Papillomas. [PDF]
Penella A +6 more
europepmc +1 more source
An in vivo assay for osteoclast activity using mouse calvaria
This study describes a novel method for measuring osteoclast‐mediated bone resorption in vivo using a mouse model. Localized injection of RANKL in a basement membrane matrix above the cranium induced osteoclast‐mediated bone resorption. Utilizing micro‐computed tomography and a semiautomated three‐dimensional analysis program, osteoclast resorption pit
Christopher Grieg +2 more
wiley +1 more source
Low Block Hybrid Rhinoplasty as a New Alternative for Mixed-Race Noses. [PDF]
Azabache R, Robles J, Segura C.
europepmc +1 more source
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Volumetric evaluation of the maxillary sinus using cone-beam computed tomography. [PDF]
Ozsoy SC +6 more
europepmc +1 more source

