Results 151 to 160 of about 73,649 (308)

Elevated Expression of Thyroid Hormone Receptor A2 (C-Erb a-A2) in Nasopharyngeal Carcinoma

, 2009
Differential display was used to identify genes differentially expressed between cultured normal nasal epithelial cells and nasopharyngeal carcinoma (NPC) cell lines.
李政偉;陳志榮;莊碧簪;陳振陽;楊照雄;董馨蓮, LEE, JENG-WOEI;CHEN, CHI-LONG;JUANG, BI -TZEN;CHEN, JEN-YANG;YANG, CZAU-SIUNG;DOONG, SHIN-LIAN   +1 more
core  

Skeletal muscle status and malnutrition as predictors of short‐term radiotherapy response and oral mucositis in head and neck cancer

Precision Radiation Oncology, EarlyView.
Baseline muscle mass and malnutrition were not decisive for short‐term radiotherapy outcomes in advanced head‐and‐neck cancer, yet diminished hand‐grip strength signaled poorer tumor response. This suggests that functional muscle metrics may serve as an accessible, actionable biomarker warranting validation in larger longitudinal cohorts.
Haomiao Zhang, Xiaonan Hu, Junying Zhao, Mingxin Zhang, Yang You, Wencheng Shao, Lili Yu   +6 more
wiley   +1 more source

Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth

, 2018
Franck Gallardo,1 Bernard Mariamé,2 Remi Gence,3 Anne-Francoise Tilkin-Mariamé4 1NeoVirTech, SAS, Institut for Advanced Technology in Life Science (ITAV), Toulouse, France; 2ITAV USR3505 CNRS/LBME, UMR 5099 CNRS, Toulouse, France; 3INSERM ...
Mariamé B, Tilkin-Mariamé AF, Gallardo F, Gence R   +3 more
core  

A new perspective on radiotherapy in the comprehensive treatment of cancer

Precision Radiation Oncology, EarlyView.
Radiotherapy remains a key component in the comprehensive management of cancer. Its effectiveness is significantly improved through strategic combinations with chemotherapy, targeted therapy, and immunotherapy, providing a range of therapeutic outcomes from cure to palliative care.
Yingze Ma, Hongxuan Yu, Shijie Shang, Shixin Shan, Dawei Chen   +4 more
wiley   +1 more source

Refining the boundaries of the nodal CTV in the middle neck for nasopharyngeal carcinoma

Precision Radiation Oncology, EarlyView.
This study proposes fascial‐based optimizations for middle neck clinical target volume (CTV) in nasopharyngeal carcinoma (NPC), excluding the para‐pharyngeal space (PPS) and adjusting boundaries to reduce radiation volume while ensuring at‐risk nodal coverage.
Yue Deng, Yi Liu, Dan Wang, Yue Zhao, Wenjun Liao, Li Yin, Jianxia Lyu, Guotai Wang, Shichuan Zhang   +8 more
wiley   +1 more source

Evolutionary role of chemotherapy in advanced nasopharyngeal carcinoma: a literature-based network meta-analysis

, 2019
Li Li,1 Wei Liang,1 Jin-Xian Zhu,1 Chun-Jie Dong,2 Yuan-Mei Zou,1 Bi-Cui Ye,1 Lin Gao1 1Department of Radiation Oncology, Wuzhou Red Cross Hospital, Wuzhou, Guangxi, People’s Republic of China; 2Department of Internal Medicine, The Second Hospital ...
Ye BC, Zou YM, Liang W, Zhu JX, Gao L, Dong CJ, Li L   +6 more
core  

Expression of the Epstein-Barr Virus Bhrf1 Gene, a Homologue of Bcl-2, in Nasopharyngeal Carcinoma Tissue

, 2008
Epstein-Barr virus (EBV) infection is associated closely with the pathogenesis of nasopharyngeal carcinoma (NPC). The EBV gene product, BHRF 1, has been demonstrated in vitro and is structurally and functionally similar to the oncogene bcl-2, that is ...
LIU, MEI-YING;LI, LONG-YUAN;SHEEN, TZUNG-SHIAHN;CHEN, CHI-LONG;YANG, CZAU-SIUNG;CHEN, JEN-YANG, 劉玫英;李龍緣;沈宗憲;陳志榮;楊照雄;陳振陽   +1 more
core  

Timing for Radiotherapy Initiation After Dental Extraction and Risk of Osteoradionecrosis in Head and Neck Cancer Patients: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) patients are advised to undergo dental extraction of teeth with poor prognosis prior to radiotherapy (RT) initiation to prevent osteoradionecrosis (ORN). However, insufficient healing time may result in persistent extraction wounds during RT, which constitute a potential risk factor for ORN, whereas ...
Nuo‐Zhou Liu, Yi‐Xuan Liu, Zhe Li, Jun Ma, Na Liu   +4 more
wiley   +1 more source

Epithelial YPEL3 Modulates CD8+ T‐Cell Infiltration and Tumor Progression Through CREB1–CXCL16 Signaling in HNSCC

Cancer Science, EarlyView.
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Yalun Li, Yumei Li, Caiyu Sun, Congxian Lu, Gang Chen, Tianshu Zhou, Bei Zhang, Xicheng Song   +7 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source