Results 101 to 110 of about 114,607 (256)

Nasopharyngeal Carcinoma: Genetics and Genomics

, 2019
This chapter introduces the genetics and genomics of nasopharyngeal carcinoma (NPC). We introduce, in brief, findings leading to the current state of knowledge of what we know about the molecular genetic basis of NPC prior to new molecular advances in ...
Lung, ML, Ko, JMY, Dai, W
core   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

Head &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun, Seyoung Seo, Jang Ho Cho, Keon‐Uk Park, Sang‐Cheol Lee, Yong Won Choi, Tak Yun, Seong Hoon Shin, Sung‐Bae Kim, Seungeun Lee, Chang Ho Ahn, Bhumsuk Keam   +11 more
wiley   +1 more source

Development of neoplasms in pediatric patients with rheumatic disease exposed to anti-tumor necrosis factor therapies: a single Centre retrospective study

Pediatric Rheumatology Online Journal, 2018
Background Anti-TNF (Tumor necrosis factor) therapy is effective in treating pediatric patients with refractory rheumatic disease. There is however a concern that anti-TNF usage may increase the risk of malignancy. Reports on specific types of malignancy
Alexandra Okihiro, Rachana Hasija, Lillia Fung, Bonnie Cameron, Brian M. Feldman, Ronald Laxer, Rayfel Schneider, Earl Silverman, Lynn Spiegel, Rae S. M. Yeung, Shirley M. L. Tse   +10 more
doaj   +1 more source

Decrease in Pneumococcal Co-Colonization following Vaccination with the Seven-Valent Pneumococcal Conjugate Vaccine [PDF]

, 2012
Understanding the epidemiology of pneumococcal co-colonization is important for monitoring vaccine effectiveness and the occurrence of horizontal gene transfer between pneumococcal strains.
Sá-Leão, Raquel, Katherine Gould, Francisco Pinto (188116), Katherine Gould (188123), Hinds, Jason, Pinto, Francisco, Kathrin Mühlemann (109266), Jason Hinds (41307), Silvio D. Brugger, Raquel Sá-Leão (188130), Carina Valente, Kathrin Mühlemann, Gould, K, Valente, C, Brugger, Silvio D., Hermínia de Lencastre, Carina Valente (188109), de Lencastre, Hermínia, Raquel Sá-Leão, Silvio D Brugger, Valente, Carina, Hinds, J, Silvio D. Brugger (109258), Pinto, F, de Lencastre, H, Sá-Leão, R, Brugger, SD, Jason Hinds, Francisco Pinto, Mühlemann, K, Hermínia de Lencastre (1970), Gould, Katherine, Mühlemann, Kathrin   +32 more
core   +2 more sources

The Role of Multicancer Early Detection Tests in Head and Neck Squamous Cell Carcinoma: A Case Series

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) lacks an established screening program, and most cases are diagnosed at advanced stages. Multi‐cancer early detection (MCED) blood‐based assays represent a promising approach, yet real‐world clinical experience with MCED‐identified HNSCC remains limited.
Abhinav Talwar, Olivia Ben‐Levy, Nikhil Sriram, Sandeep Samant   +3 more
wiley   +1 more source

The Tubarial Glands Mystery: Shifting Paradigms from Hidden Anatomy to Clinical Significance

Surgeries
Background/Objectives: This paper synthesizes and evaluates the potential origins of ectopic salivary gland pathologies in the human nasopharynx. By combining historical reports with an original comparative analysis, this study aims to clarify the ...
Bistra Blagova, Georgi Tomov
doaj   +1 more source

Nasopharyngeal (Tornwaldt’s) Cyst: Rare Finding in a Habitual Snorer [PDF]

, 2012
A nasopharyngeal (tornwaldt’s) cyst is uncommon. It is often asymptomotic; however it may cause problem if it too big becomes. We present a case of a 24-year-old Malay girl who had been a habitual snorer for years but was unaware of the significance of ...
Ng WSJ, Sinnathuray AR
core  

Parotid Gland Mass as the Presenting Symptom of Nasopharyngeal Carcinoma [PDF]

, 2014
Even though metastatic tumors of the parotid gland are rarely seen, they are observed more frequently than other salivary gland metastatic masses. The reason why this gland is more frequently affected by metastatic tumors as compared to other salivary ...
Özge Düzcı Yüksel, Düzci Yüksel, Özge, Çiğdem Tepe Karaca, Verim, Ayşegül, Barış Naiboğlu, Çalım, Ömer Faruk, Naibo?lu, Barış, Ayşegül Verim, Ömer Faruk Çalım, Tepe Karaca, Çi?dem   +9 more
core   +1 more source

Exploring the Effects of Frailty and Sarcopenia on Dysphagia in Head and Neck Cancer: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Frailty and sarcopenia may influence head and neck cancer (HNC) treatment outcomes, including dysphagia. Current understanding of this relationship, however, remains limited. This scoping review aimed to synthesize existing evidence on the relationship between frailty and/or sarcopenia and dysphagia in adults with HNC.
Rishni Perera, Elizabeth C. Ward, Nicole O'Donnell, Paul Yates, Rebecca L. Packer   +4 more
wiley   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Travis, W., Beuschlein, Felix, Karl, M., Chrousos, G. P., Abdelhamid, S., Allolio, B., Jaursch-Hancke, C., Reincke, Martin   +7 more
core   +1 more source