Results 221 to 230 of about 30,002 (370)

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Association of Matrix Metalloproteinase-7 Genotypes With Nasopharyngeal Carcinoma Risk. [PDF]

open access: yesIn Vivo
Shih LC   +9 more
europepmc   +1 more source

Induction Camrelizumab and Modified TPF (Nab‐Paclitaxel, Cisplatin, and S‐1) in Locoregionally Advanced Nasopharyngeal Carcinoma

open access: yesCancer Science, EarlyView.
ABSTRACT Induction chemo‐immunotherapy has emerged as a potential treatment option for locoregionally advanced nasopharyngeal carcinoma (LANPC). This study aimed to evaluate the efficacy and safety of camrelizumab combined with modified TPF (nab‐paclitaxel, cisplatin, and S‐1) as induction chemo‐immunotherapy in LANPC.
Yi‐Feng Yu   +5 more
wiley   +1 more source

Claudin‐11 Enhances Invasive and Metastatic Abilities of Small‐Cell Lung Cancer Through MT1‐MMP Activation

open access: yesCancer Science, EarlyView.
Claudin‐11 is a tight junction protein, and its role in small‐cell lung cancer (SCLC) remains unclear. This study showed that claudin‐11 was significantly upregulated in a highly metastatic subline of DMS273 SCLC cells, promoting cell invasion and metastasis through the activation of MT1‐MMP. Furthermore, claudin‐11 expression was detected in some SCLC
Shuichi Sakamoto   +9 more
wiley   +1 more source

LTF as a Potential Predictive Biomarker for Durable Benefit From First‐Line Chemo‐Immunotherapy in Small Cell Lung Cancer

open access: yesCancer Science, EarlyView.
LTF as a potential biomarker for predicting the efficacy of chemo‐immunotherapy. ABSTRACT At present, only a limited fraction of patients with extensive‐stage small cell lung cancer (ES‐SCLC) achieve a sustained response to immune checkpoint blockade (ICB) therapy.
Shimo Shen   +7 more
wiley   +1 more source

The role and mechanism of aerobic glycolysis in nasopharyngeal carcinoma. [PDF]

open access: yesPeerJ
Pan Z   +10 more
europepmc   +1 more source

PSMD14/E2F1 Axis‐Mediated CENPF Promotes the Metastasis of Triple‐Negative Breast Cancer Through Inhibiting Ferroptosis

open access: yesCancer Science, EarlyView.
PSMD14/E2F1 axis‐mediated CENPF could promote the metastasis of BC through inhibiting arachidonic acid metabolism‐induced ferroptosis. This research might bring novel insights on discovering methods in alleviating tumor metastasis in BC. ABSTRACT The metastasis of triple‐negative breast cancer (TNBC) usually contributes to the failure of treatment ...
Meifeng Zhou   +4 more
wiley   +1 more source

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