Results 111 to 120 of about 339,595 (303)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
China's Belt and Road Initiative Implementation Maneuvers in the South Pacific Region
Nation StateThe geopolitical ascendancy of China's Belt and Road Initiative (BRI) within the South Pacific Region has been extensively scrutinized due to its potential to both align with global development agendas and provoke sovereignty concerns among recipient ...
Rezya Agnesica Helena Sihaloho +2 more
doaj +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Move Closer! New Modes of Governance and Accession to the European Union [PDF]
This paper focuses on new modes of governance in the EU’s attempts to impact upon states, which are not (yet) members and which have become members in the 1980s.
Tanja A. Börzel
core
Achieving National Economic and Social Goals: The Counterproductive Role of Post-1965 Immigration Policy [PDF]
, 1995 [Excerpt] Immigration is a discretionary policy of every nation state. No citizen of any foreign nation has a right to enter any other country for the purpose of permanent settlement or for employment just because he or she wishes to do so.
Briggs , Vernon M. , Jr.
core +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Transition from socialism [PDF]
This paper discusses the changes that socialist countries, specially in Eastern Europe, are currently undergoing. It also comments on the decline all over the world of the institution of the nation-state, and, particularly, a decline in its importance in
Kenneth J. Arrow
core
The nation-state, class, digital divides and social anthropology. [PDF]
Soc Anthropol, 2020 Gellner DN.
europepmc +1 more source