Results 161 to 170 of about 134,758 (266)

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Motivations for Nonuse as Predictors of Substance Use Among Reservation-Based Youth in a Computerized Screening and Brief Intervention: The Power of Positive People. [PDF]

J Child Adolesc Subst Use
Barry CM, Livingston MD, Atkinson E, Skinner JR, Komro KA.   +4 more
europepmc   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

Advanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng, Cinzia Esposito, Andrej Benjak, Matthias S. Matter, Miriam Cieri, Camilla De Carlo, Philipp Sedlaczek, Fabian Haak, Mattia Marinucci, Gabriel Fridolin Hess, Otto Kollmar, Mairene Coto‐Llerena, Luca Di Tommaso, Visar Vela, Lukas Bubendorf, Luigi M. Terracciano, Charlotte K. Y. Ng, Salvatore Piscuoglio   +17 more
wiley   +1 more source

Bivalent RSV prefusion vaccine effectiveness against hospitalisation in older adults: meta-analysis of case-control studies in England, Wales, Scotland, and Northern Ireland. [PDF]

Lancet Reg Health Eur
Bucholc M, Hameed SS, Cottrell S, Mensah AA, Morrison K, Whitaker HJ, Borjas-Howard J, Cobbold A, Marsh K, McQueenie R, Andrews N, O'Doherty MG, Dickson E, Robertson C, McClure V, Rubeshkumar P, Brown C, Menadue J, Johnson C, Perry M, Kalapotharakou P, Barry M, Moore C, Zitha J, Ghebrehewet S, McMenamin J, Williams CJ, Watson CH, Bradley DT.   +28 more
europepmc   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Virtual deliberation on genetics research: report-out of key themes from Diné (Navajo) research & healthcare professionals. [PDF]

J Community Genet
Sherman CA, Nez LC, Aagaard KM, Livingston DJ, Blacksher E, Reedy J, Hiratsuka VY, Phelps W, Blanchard JW, Lund JR, Beans JA, Nez FL, Garrison NA, Claw KG.   +13 more
europepmc   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Implications of Medicare Negotiation and Most-Favored-Nation Pricing for Cancer Medicine Costs.

JAMA Health Forum
Hwang TJ, Tibau A, Kesselheim AS, Vokinger KN.   +3 more
europepmc   +1 more source

Childhood Trauma and Adult Loneliness as Predictors of Sleep Health in Blackfeet American Indian Adults. [PDF]

Int J Behav Med
Hutchison M, Henderson-Matthews B, Wood ZJ, Kothe R, Runner GH, Johnson Iii L, Lafromboise ME, Malatare M, Salois E, Carter JR, Helm P, John-Henderson NA.   +11 more
europepmc   +1 more source

Achieving High‐Density and Stress‐Resilient Maize Breeding Via Germplasm Innovation

Advanced Science, EarlyView.
Global population growth and climate change have exacerbated the global food crisis. This perspective presents a conceptual framework focusing on enhancing population advantages. Several novel breeding objectives are proposed to improve density tolerance and stress resistance for yield improvement.
Xinlong Li, Yongqiang Chen, Dong Ding, Xuehai Zhang, Xuxiang Jia, Zhanhui Zhang, Yafei Wang, Weihua Li, Hui Zhang, Jihua Tang   +9 more
wiley   +1 more source