Results 121 to 130 of about 585,033 (287)
Comment on Understanding PPPs and PPP Based National Accounts [PDF]
The paper discusses the three major problems that Deaton and Heston identify that make it difficult to construct consistent estimates of real output across countries: (i) the choice of a multilateral index number formula; (ii) weak national accounts ...
Diewert, Erwin
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Benford's Law and Possibilities for Its Use in Governmental Statistics [PDF]
Statistika: Statistics and Economy Journal, 2015 Benford's Law (sometimes also called Benford's Distribution or Benford's Test) is one of the possible tools for verification of a data structure in a given file regarding the relative frequencies of occurrence of the fi rst (or second, etc.) digit from ...
Richard Hindls, Stanislava Hronová
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
National Health Accounts in Latin America and Caribbean - Concept, Results and Policy Uses [PDF]
This paper presents the National Health Accounts (NHA) methodology and its relevance in policy making in the Latin American and Caribbean (LAC) region. After presenting the concept of NHA and highlighting recent results of LAC data collection activities,
Alessandro Magnoli
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Medical Savings Accounts in Singapore: How much is adequate? [PDF]
While many studies have examined the cost-containment aspect of Medical savings accounts (MSA), few have investigated the adequacy of MSA to finance the health care expenditure. This paper estimates the present value of lifetime healthcare expenses (PVHE)
Albert K C Tsui, Ngee-Choon Chia
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source