Results 61 to 70 of about 585,033 (287)
Relevance. Personnel crisis and demographic challenges. The authors conduct a comprehensive analysis of the factors influencing the effectiveness of mentoring, based on the historical example of the Hawthorne Experiment (1924–1932), which first ...
Olga P. Nedospasova, Eduard B. Seletsky
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The article examines requirements and methodological approaches to the calculation of price indices (deflators) in the national accounts. It gives estimation for the level and dynamics of price indicators.
K. Prykhodko
doaj +1 more source
Methodological Features of GDP Formation Within the Framework of the System of National Accounts
Purpose of the study. The aim of this work is to examine methodological approaches to the formation of gross domestic product on an annual and quarterly basis within the framework of the System of National Accounts, using the example of 189 countries ...
K. A. Alekseev
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
NATIONAL ACCOUNTS OF ROBINSON ́S ECONOMY [PDF]
The system of national accounts provides data for economic analysis, especially analysis of business cycle. While properties of time series are continually under discussion, much less formation and predicative ability of the aggregates. Aim of this paper
Vaclav Rybacek
core
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Data on Economic Analysis: 2017 Social Accounting Matrices (SAMs) for South Africa
The purpose of the Social Accounting Matrix (SAM) is to improve the quality of the database for modelling, including, but not limited to, policy analysis, multiplier analysis, price analysis, and Computable General Equilibrium.
Ramigo Pfunzo +2 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source

